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The upcoming NFL clash between the Houston Texans and Jacksonville Jaguars on September 21, 2025, promises to be a thrilling encounter at EverBank Stadium in Jacksonville, FL. This match marks Week 3 of the 2025-26 NFL season. As fans gear up for this exciting contest, the current odds favor the Jacksonville Jaguars with a point spread of -1½ -110, while the Texans are at +1½ -110, both available at Caesars. The Moneyline odds have the Jaguars at -122 and the Texans at +100. Bettors can catch the action live on CBS and make informed decisions by exploring the latest betting lines and odds changes. For those looking to gain an edge, Start your OddsTrader Turbo subscription for expert insights. The opening odds saw the Jaguars as slight favorites, reflecting their home advantage at EverBank Stadium. For more detailed odds analysis, visit our NFL odds page. Don't miss this opportunity to place a well-informed wager with a U.S. regulated sportsbook and enjoy Sunday football at its best.
Buffalo 2-019% -11½ -114FanDuel | |||||||
![]() Tennessee 0-283% +4½ -118Caesars | |||||||
Carolina 0-285% +6 -115BetMGM | |||||||
![]() Washington 1-121% -3 -115FanDuel | |||||||
Cleveland 0-285% +8 -110BetMGM | |||||||
Minnesota 1-149% -3 -105BetMGM | |||||||
Philadelphia 2-041% -3½ -104FanDuel | |||||||
New England 1-160% +2 -113BetRivers | |||||||
![]() Tampa Bay 2-026% -6½ -115Caesars | |||||||
Jacksonville 1-158% -1½ -110Bet365 | |||||||
![]() L.A. Chargers 2-030% -2½ -117BetRivers | |||||||
Seattle 1-19% -7½ -105FanDuel | |||||||
![]() Chicago 0-280% +1 -110Caesars | |||||||
![]() San Francisco 2-056% -2½ -112BetRivers | |||||||
![]() N.Y. Giants 0-277% +6½ -110BetMGM | |||||||
![]() Baltimore 1-127% -4½ -110Caesars |
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