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The upcoming NFL showdown on January 4, 2026, between the Arizona Cardinals and the L.A. Rams at SoFi Stadium in Inglewood, CA, promises to be a thrilling Sunday football matchup. Both teams will look to leverage their strengths heading into this Week 18 regular-season game broadcasted on FOX.
The Cardinals, led by starting quarterback Kedon Slovis, face a tough challenge against the Rams' defense. Arizona's passing offense, averaging 232.3 yards per game, will be tested against a Rams defense that allows just 215.4 passing yards per game. On the ground, the Cardinals rush for 94 yards per game while the Rams allow 125.6 rushing yards. The Rams, with Matthew Stafford under center, boast a potent offense averaging 394.6 total yards per game, including 269 passing yards and 125 rushing yards, matched against a Cardinals defense giving up 355 total yards. The Rams' ability to protect Stafford against the Cardinals' pass rush will be a key factor.
The Rams enter as 7.5-point favorites with a total points line set at 46.5. Their strong home record of 6-1 and 5-2 ATS at home, compared to the Cardinals' 2-6 away record and 5-3 ATS away, suggests a betting edge. Betting trends from their last matchup on December 7, 2025, where the Rams won decisively 45-17, also support the Rams. The game insights indicate a high-scoring potential, but the under is favored by oddsmakers.
Injuries could impact the game, with the Cardinals listing several questionable players including cornerback Will Johnson and wide receiver Marvin Harrison Jr., while the Rams have some doubts with Davante Adams doubtful and offensive lineman Alaric Jackson questionable. These factors could influence offensive rhythm and defensive matchups.
For bettors looking to capitalize on this exciting matchup, understanding the betting trends and stats will be crucial. The Rams' home dominance and offensive firepower make them the best bet. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Tampa Bay 7-942% -2½ -115Bet365 | |||||||
![]() San Francisco 12-440% +1½ -110Bet365 | |||||||
Minnesota 8-856% -5½ -120FanDuel | |||||||
![]() Houston 11-537% -10 -112BetRivers | |||||||
![]() Cincinnati 6-1027% -7½ -109Caesars | |||||||
![]() N.Y. Giants 3-1378% +3½ -110Bet365 | |||||||
![]() Atlanta 7-955% -3 -114Caesars | |||||||
Jacksonville 12-433% -12 -115SugarHouse | |||||||
New England 13-39% -10½ -110Caesars | |||||||
![]() Las Vegas 2-1433% +6 -117SugarHouse | |||||||
![]() Chicago 11-533% -2½ -117BetRivers | |||||||
Buffalo 11-54% -7 -110Bet365 | |||||||
Philadelphia 11-510% -7 -110Bet365 | |||||||
![]() L.A. Rams 11-527% -7 -110Bet365 | |||||||
Denver 13-328% -11½ -110FanDuel | |||||||
![]() Pittsburgh 9-779% +3½ -113Caesars |
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