Arizona Cardinals vs L.A. Rams Rams Betting Trends

The upcoming NFL showdown on December 7, 2025, features the Arizona Cardinals vs L.A. Rams Rams at State Farm Stadium in Glendale, AZ. This Sunday football game, broadcast on FOX, offers compelling betting trends and game insights for savvy bettors. The Cardinals will start backup quarterback Jacoby Brissett, as star Kyler Murray remains on injured reserve with a foot injury. The Rams will counter with starter Matthew Stafford, giving them a quarterback advantage that could influence the passing game significantly.

Arizona's offense averages 236.7 passing yards and 100.6 rushing yards per game, but they face a tough Rams defense that allows just 207.3 passing yards and 107.8 rushing yards on average. Meanwhile, the Rams offense is strong with 246.6 passing yards and 113.5 rushing yards per game, matched against a Cardinals defense yielding 219.6 passing yards and 112.6 rushing yards. The Rams also benefit from a stronger pass protection line versus the Cardinals' aggressive pass rush, which can impact the game's flow and betting outcomes.

The current odds favor the Rams with a -8.5 point spread and an over/under total points line of 47.5. Bettors should consider the Rams' home field advantage and recent form, as well as the Cardinals' injury challenges, including key defensive and offensive players out or questionable. The Rams have a 9-3 straight-up record and 8-4 against the spread, while the Cardinals sit at 3-9 straight up and 6-6 ATS, making the Rams a strong pick for this Sunday football clash.

In their last matchup on December 28, 2024, the Rams edged the Cardinals 13-9 at SoFi Stadium, a close game that went under the total points line of 48. This history, combined with current betting trends and stats, offers crucial sports insights to help bettors make informed wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.