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The highly anticipated Monday night football clash on December 1, 2025, between the N.Y. Giants Giants and the New England Patriots at Gillette Stadium in Foxborough, MA, is set to draw significant attention in the NFL. This game offers valuable betting trends that bettors should not overlook. The Giants, with a 7-5 ATS record and several key players questionable or injured, face the Patriots, who boast a strong 8-4 ATS record and a solid home performance.
Starting quarterbacks Jaxson Dart for the Giants and Drake Maye for the Patriots will be pivotal. Dart, a younger QB, faces a Patriots defense that ranks strong in pass rush, putting pressure on the Giants' pass protection, which has some vulnerabilities. Meanwhile, the Patriots' offense, averaging 247.5 passing yards, will test the Giants' defense, which allows 227.8 passing yards on average. The Patriots' run offense, averaging 112.4 yards, will also challenge the Giants' run defense that gives up 157.2 yards per game, suggesting the Patriots might exploit the ground game advantage.
The point spread sits at 7 points favoring the Patriots, with a total points line at 46.5. These odds indicate a moderately expected win margin for the Patriots but also point to a potentially competitive game. Betting insights suggest leaning towards the Patriots to cover the spread considering their strong home record and recent form. The Giants have struggled with injuries on defense, which could impact their ability to stop the Patriots' dynamic offense.
This matchup is broadcasted on ESPN, providing fans and bettors the opportunity to watch the game live while following the latest betting trends. For those looking to make informed bets, reviewing the comprehensive game stats and betting trends can provide an edge. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
In their last matchup on August 21, 2025, the Giants were defeated by the Patriots 42-10 at MetLife Stadium, a game that highlighted the Patriots' offensive dominance and defensive resilience.
Philadelphia 8-335% -7 -109Caesars | |||||||
![]() Indianapolis 8-350% -3½ -109Caesars | |||||||
![]() Tampa Bay 6-532% -2½ -120SugarHouse | |||||||
![]() Tennessee 1-1055% +6½ -114FanDuel | |||||||
Carolina 6-660% +10½ -110FanDuel | |||||||
Miami 4-729% -5½ -110Bet365 | |||||||
![]() N.Y. Jets 2-973% +3 -125BetMGM | |||||||
Cleveland 3-829% +5 -110FanDuel | |||||||
Seattle 8-354% -10½ -105FanDuel | |||||||
![]() Pittsburgh 6-577% +3½ -115Caesars | |||||||
![]() L.A. Chargers 7-418% -9 -115SugarHouse | |||||||
![]() Washington 3-835% +6 -114BetRivers | |||||||
New England 10-222% -7 -109Caesars | |||||||
Detroit 7-524 -3 -105BetMGM | |||||||
Dallas 6-5-131 +3½ -110BetMGM | |||||||
![]() Baltimore 6-614 -7½ -114BetRivers |
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