Betting Trends Arizona Cardinals vs Tampa Bay Buccaneers

The upcoming NFL clash on November 30, 2025, features the Arizona Cardinals visiting the Tampa Bay Buccaneers at Raymond James Stadium in Tampa, FL. This Sunday football game is set to be broadcasted on FOX, offering fans and bettors an exciting matchup to watch and wager on. The Cardinals, currently with a 3-8 record straight up and a 5-6 ATS record, will face a Buccaneers team holding a 6-5 straight-up record and matching 5-6 ATS. Arizona's offense averages 332.8 total yards per game with a solid passing attack, while Tampa Bay boasts a slightly higher total yardage of 341.2 per game and a robust defense.

Starting quarterbacks will play a pivotal role in this game. While Arizona’s Kyler Murray remains on injured reserve, backup quarterback Jacoby Brissett is expected to start, which could influence the Cardinals' offensive rhythm. Tampa Bay's quarterback situation is somewhat uncertain with Baker Mayfield listed as questionable but likely to play, providing the Buccaneers with a potential edge in passing offense. The Buccaneers' defense is known for applying pressure, which could challenge Arizona's offensive line, especially with some key injuries on the Cardinals' offensive front.

Betting trends show Tampa Bay favored by 3 points with a total points line set at 44.5. The Buccaneers have been strong at home but have a weaker ATS home record (1-3), whereas Arizona has a better ATS away record (4-1). This contrast suggests bettors should consider the point spread carefully. The matchup highlights a battle between Tampa Bay's pass rush and Arizona’s pass protection, which could be decisive for the game's outcome.

Fans can leverage these betting insights and stats to make informed wagers. The Buccaneers' balanced offense and home-field advantage, combined with the Cardinals' injury challenges, make Tampa Bay a compelling pick against the spread. The best odds for Tampa Bay are currently -3 at Caesars, and bettors can find similar offers at other U.S. regulated sportsbooks. For a deeper dive into the numbers and to sharpen your betting strategy, Start your OddsTrader Turbo subscription or place your bet with a trusted sportsbook today.

Don't miss the chance to revisit their last matchup on December 25, 2022, where Tampa Bay edged Arizona 19-16, which was a close contest that could provide valuable context for this upcoming battle.