Carolina Panthers vs Atlanta Falcons Betting Trends

The upcoming NFL matchup on November 16, 2025, between the Carolina Panthers and the Atlanta Falcons at Mercedes-Benz Stadium in Atlanta, GA, promises an exciting Sunday football showdown. This game offers valuable betting trends and game insights for bettors looking to gain an edge.

Carolina Panthers, with a 5-5 straight-up record and 6-4 against the spread, face the Falcons who hold a 3-6 straight-up record and a 5-4 ATS record. The Panthers are slight underdogs with a +3.5 point spread, while the Falcons are favored at -3.5, and the total points line is set at 42.5, favoring the under.

Carolina's starting quarterback is Bryce Young, who has shown solid performances, especially against Atlanta, including a 30-0 win in their last matchup on September 21, 2025. Atlanta's Michael Penix Jr. will start under center, but the Falcons have several key players listed as questionable, including Chris Lindstrom (foot) and Mike Hughes (neck), which could impact their offensive and defensive line effectiveness.

Analyzing the pass and run offenses versus defenses, Carolina's pass offense averages 164 yards against Atlanta's pass defense of 162 yards allowed per game, suggesting a balanced passing game battle. Atlanta's rushing offense is slightly less productive at 119 yards compared to Carolina's run defense allowing 111 yards, indicating a tough ground game ahead. The Falcons' pass protection versus Panthers' pass rush will be critical, especially with Atlanta's offensive line facing injury concerns.

Bettors should consider the Panthers' recent strong ATS performance and the Falcons' home advantage. The Panthers' ability to control the game tempo and the Falcons' defensive vulnerabilities offer intriguing betting insights. For the best betting trends and odds, check out the latest lines at Caesars with Falcons favored at -3.5 and the under at 42.5 points. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

In their last matchup on September 21, 2025, the Panthers defeated the Falcons 30-0, showcasing their dominance that bettors should consider heading into this game.