Buffalo Bills vs Denver Broncos Betting Trends

The highly anticipated Saturday football matchup on January 17, 2026, features the Denver Broncos hosting the Buffalo Bills at Empower Field at Mile High in Denver, CO. This NFL showdown offers intriguing betting trends and game insights for bettors looking to capitalize on the action. Denver's starting quarterback will be Jarrett Stidham, while Buffalo will rely on their star QB Josh Allen, who is fully participating in practice despite minor injury concerns. Allen's dynamic playmaking ability gives the Bills a slight edge in the quarterback matchup.

Analyzing the teams' offense and defense, the Buffalo Bills boast a potent passing offense averaging 216.6 yards per game, matched against Denver's defense allowing 187.2 passing yards on average. The Bills' run offense is also strong at 159.6 yards per game, facing a Broncos run defense that limits opponents to just 91.1 yards. However, Denver's pass rush, with 4 sacks per game, challenges Buffalo's pass protection, which allows 2.5 sacks on average. This clash of strengths and weaknesses sets the stage for a tactical battle.

The Broncos hold an impressive 14-3 straight-up record, especially strong at home with an 8-1 mark, while Buffalo is 13-5 overall and 6-3 on the road. Against the spread, the Bills are 9-9, and the Broncos 7-10, with both teams having similar ATS home/away splits. The betting line favors Buffalo by 1.5 points, with a total set at 46.5 points, indicating a moderately close game. This spread and total suggest bettors should consider the defensive capabilities and recent form when placing wagers.

Buffalo's recent form includes a narrow 27-24 win over Jacksonville, while Denver comes off a 19-3 victory over the Chargers. Key injuries for Buffalo include questionable status for DE Joey Bosa and RB Ty Johnson, while Denver's lineup appears healthy. The game will be broadcast on CBS, giving fans nationwide access to this exciting contest. These betting insights and stats can help bettors make informed decisions and find value in the wagering markets. For the best odds on this game, consider checking BetOnline.

In their last matchup on January 12, 2025, the Bills dominated the Broncos 31-7, covering the spread comfortably. This history adds context to the betting trends and expectations for this upcoming game.