- Spread
- Money
- Total
- Merged
The upcoming NFL showdown on Thursday night football, November 20, 2025, features the Buffalo Bills vs Houston Texans at NRG Stadium in Houston, TX. This highly anticipated Week 12 regular season matchup will be broadcast on Amazon Prime Video, giving fans and bettors plenty to be excited about. The injury report for this game is crucial for bettors looking to make informed wagers.
The Buffalo Bills enter this game with significant injury challenges. Key wide receivers Curtis Samuel and Mecole Hardman are both ruled out due to elbow and calf injuries, respectively, sidelining important offensive weapons. Safety Taylor Rapp is on injured reserve with a knee injury and is expected to miss the rest of the season, which could impact the Bills' defensive stability. Other notable injuries include kicker Tyler Bass on IR with a hip injury, defensive end Michael Hoecht out for the season with a torn Achilles, and safety Damar Hamlin also on IR. Tight end Dalton Kincaid is out with a hamstring injury, further limiting offensive options. Defensive tackle Ed Oliver is on injured reserve but may return for the playoffs, while Phidarian Mathis is questionable with a shoulder injury.
On the Houston Texans side, running back Joe Mixon is on the NFI list with a foot injury, and safety Jimmie Ward is on the PUP list, with both players' return timelines uncertain but hopeful. Other key injuries include safety M.J. Stewart on injured reserve (quadriceps), defensive tackle Folorunso Fatukasi on IR (shoulder), wide receiver Justin Watson on IR (Achilles), and defensive end Darrell Taylor on IR (ankle). Quarterback C.J. Stroud is out with a concussion, a significant blow to the Texans' offense. Tight ends Harrison Bryant and Brevin Jordan are also on IR, affecting the Texans' passing game. Safety Jalen Pitre is out with a concussion, and linebacker Jamal Hill is ruled out due to a hamstring injury.
These injuries will undoubtedly impact both teams' strategies and performance. Bettors should pay close attention to the injury statuses as they can influence game dynamics and betting odds. For the latest updates and a comprehensive view, check the NFL injury report page for detailed player statuses and injury lists. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Chicago 7-352% -2½ -114Caesars | |||||||
![]() Baltimore 5-515% -13 -115SugarHouse | |||||||
Detroit 6-47% -10½ -102FanDuel | |||||||
![]() Cincinnati 3-767% +7 -115Bet365 | |||||||
![]() Tennessee 1-986% +13½ -112FanDuel | |||||||
Green Bay 6-3-123% -6½ -109Caesars | |||||||
![]() Kansas City 5-526% -3 -120Bet365 | |||||||
Arizona 3-760% +3 -110Caesars | |||||||
![]() Las Vegas 2-857% -3½ -118FanDuel | |||||||
New Orleans 2-867% +1 -115Bet365 | |||||||
Dallas 4-5-137% +3½ -118BetRivers | |||||||
![]() L.A. Rams 8-237% -6½ -110Bet365 | |||||||
![]() San Francisco 7-413% -7 -110Caesars | |||||||
![]() Houston 6-523 +5½ -115SugarHouse |
OddsTrader uses cookies to help us provide, protect & improve our services. See ourPrivacy Policyfor more details.
ACCEPT & CLOSE