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Nov 20, 2025 8:15 PM EST
BUF 19 vs HOU 23
Week 12
BUF
-4½ (-115)o44½ (-110)
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Buffalo Bills vs Houston Texans Betting Trends
Updated:Nov 20, 2025 1:11 AM EST
The upcoming Thursday night football game on November 20, 2025, features the Buffalo Bills vs Houston Texans at NRG Stadium in Houston, TX, in the NFL league. This match-up offers key betting trends and exciting game insights for bettors looking to capitalize on the clash. Buffalo Bills will start their star quarterback Josh Allen, who has been performing strongly, while Houston Texans will rely on Davis Mills as their starting quarterback, with C.J. Stroud ruled out due to concussion.
Buffalo's offense boasts an average of 239.8 passing yards and 147.6 rushing yards per game, supported by a strong pass protection line. Meanwhile, Houston's defense allows 171 passing yards and 87 rushing yards on average, which could favor the Bills' passing game. On the other hand, Houston's offense averages 222 passing yards and 107.6 rushing yards, but Buffalo's defense is tight, allowing just 169.7 passing yards and 153 rushing yards per game. This dynamic sets up an intriguing battle of pass offense vs pass defense and run offense vs run defense.
The point spread is set at Buffalo Bills -6 with a total points line of 43.5, indicating a moderately high-scoring game. Buffalo's recent form includes a big win over Tampa Bay Buccaneers (44-32), but a loss against Miami Dolphins (13-30). Houston comes off a close win against Tennessee Titans (16-13). Injuries for Buffalo include key defensive players on IR and some questionable starters, while Houston has multiple players out or on IR, including starting QB Stroud.
These betting trends and game stats suggest Buffalo Bills may cover the spread given their offensive edge and starting QB advantage. The Texans' defense struggles against the pass, which Josh Allen can exploit. The game will broadcast on Amazon Prime Video, making it accessible for viewers. For bettors wanting to dive deeper, the last matchup on October 6, 2024, saw Houston edging out Buffalo 23-20 in a tight game, which you can review for additional insights.
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All
5-6 (22nd)Against the Spread5-6 (20th)
7-4 (8th)Straight Up6-5 (17th)
-0.6Straight Up Units-0.1
5-6Over / Under4-7
OFF
DEF
OFF
DEF
28.3Points22.1
13.5First Half10.6
14.8Second Half11.6
6.2First Quarter2.9
7.3Second Quarter7.6
6.8Third Quarter3.6
8Fourth Quarter8
381.8Total Yards323.4
6.6Yards Per Play5.4
234.6Passing Yards215.7
21 - 30.3 (69.4%)Completions-Attempts22.6 - 35.6 (63.5%)
7.1Yards Per Passing Play5.7
2.5 (17)Sacks (Yards)2.3 (19)
147.2Rushing Yards107.6
29.5Attempts25.9
5Yards Per Rush4.2
21.61st Downs18.9
11.8Passing11.2
7.6Rushing5.4
2.2Penalties2.4
5.3 / 12.2 (43.3%)3rd Down4.6 / 13.5 (34.5%)
0.7 / 1.4 (53.3%)4th Down1 / 1.5 (64.7%)
2.2 / 3.5 (63.2%)Red Zone1.4 / 3.1 (44.1%)
6.7 (56.1)Penalties (Yards)7 (57.2)
1.2Turnovers1.4
0.6Interceptions1.1
0.5Fumbles Lost0.3
62.4Total Plays63.8
5.7Kickoffs5.3
4.2Returns2.9
119.5Return Yards72.9
28.6Yards Per Return25.1
3.1Punts4.4
2Returns2.4
10.4Return Yards24.5
5.2Yards Per Return10.3
PRIORITYDalton Kincaid
INACTIVE
86 Tight End
PRIORITYJoe Mixon
NFI-R
28 Running Back
PRIORITYC.J. Stroud
INACTIVE
7 QB
HEAD TO HEAD
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NFLWeek 12
 Chicago 7-352% -2½ -114Caesars | |||||||
 Baltimore 5-515% -13 -115SugarHouse | |||||||
 Detroit 6-47% -10½ -102FanDuel | |||||||
 Cincinnati 3-767% +7 -115Bet365 | |||||||
 Tennessee 1-986% +13½ -112FanDuel | |||||||
 Green Bay 6-3-123% -6½ -109Caesars | |||||||
 Kansas City 5-526% -3 -120Bet365 | |||||||
 Arizona 3-760% +3 -110Caesars | |||||||
 Las Vegas 2-857% -3½ -118FanDuel | |||||||
 New Orleans 2-867% +1 -115Bet365 | |||||||
 Dallas 4-5-137% +3½ -118BetRivers | |||||||
 L.A. Rams 8-237% -6½ -110Bet365 | |||||||
 San Francisco 7-413% -7 -110Caesars | |||||||
 Houston 6-523 +5½ -115SugarHouse |
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