Buffalo Bills vs Jacksonville Jaguars Betting Trends

The upcoming NFL showdown on January 11, 2026, features the Buffalo Bills visiting the Jacksonville Jaguars at EverBank Stadium in Jacksonville, FL. This Sunday football game kicks off at 1:00 PM ET and will be broadcast on CBS. Fans and bettors will be keenly watching to see if the Bills can overcome the Jaguars on their home turf.

Buffalo's starting quarterback, Josh Allen, is listed as questionable but likely to play, which could be a significant factor in the game's outcome. Mitchell Trubisky stands ready as the backup. Jacksonville will rely on Trevor Lawrence to lead their offense. The Bills have a strong passing offense, averaging 216.6 yards per game, facing a Jaguars defense allowing 218 passing yards. Jacksonville's run defense, holding opponents to just 85.6 yards per game, could challenge Buffalo's rushing attack averaging 159.6 yards.

Buffalo's pass protection has been solid, but they face a formidable Jaguars pass rush that averages 1.88 sacks per game. The Jaguars' offense, with 337.4 total yards per game, contrasts with the Bills' defense that limits opponents to 293.1 yards. The game odds favor Buffalo by 1 point with a total of 52.5 points, suggesting a close contest. The Bills' recent 47-10 victory over Jacksonville on September 23, 2024, sets an intriguing backdrop for this rematch.

Jacksonville holds a strong home ATS record of 7-2, while Buffalo is balanced at 4-4 away against the spread. Bettors should consider these betting trends, recent performances, and injury updates to make informed wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.