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The upcoming NFL matchup between the Buffalo Bills and New England Patriots is set for December 14, 2025, at Gillette Stadium in Foxborough, MA. This Sunday football game promises to be a thrilling contest as both teams look to gain an edge in the 2025-26 NFL season. The current odds favor the Buffalo Bills as the favorites with a point spread of -1 -108, while the New England Patriots are the underdogs at +1 -112, according to Caesars. Opening odds showed a balanced line, but the Bills have gained slight momentum, which bettors should consider when evaluating the betting lines. Over/under totals are set at 49.5, with the over priced at -114 and the under at -106, indicating an expectation of a moderately high-scoring game.
Watching this game on CBS will add to the excitement, and bettors can use the latest odds provided here to make informed decisions. Understanding how the odds have shifted from the opening lines helps in spotting value bets. The venue, Gillette Stadium in Foxborough, MA, offers a classic outdoor football atmosphere that could influence gameplay and scoring. For those interested in detailed NFL betting odds, checking out the comprehensive NFL odds page is highly recommended. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Tampa Bay 7-637% -4 -110Bet365 | |||||||
![]() Houston 8-517% -9½ -110Caesars | |||||||
Philadelphia 8-519% -10½ -110Bet365 | |||||||
Jacksonville 9-426% -11½ -112BetRivers | |||||||
![]() Chicago 9-47% -7½ -110Caesars | |||||||
New England 11-253% +1½ -115FanDuel | |||||||
![]() Cincinnati 4-933% +2½ -105FanDuel | |||||||
![]() Kansas City 6-765% -4½ -110Bet365 | |||||||
![]() N.Y. Giants 2-1145% -2 -110Bet365 | |||||||
Seattle 10-311% -13½ -109Caesars | |||||||
Denver 11-218% +2½ -110Caesars | |||||||
New Orleans 3-1055% +3 -121SugarHouse | |||||||
![]() L.A. Rams 10-350% -5½ -110Bet365 | |||||||
![]() San Francisco 9-47% -12½ -110Bet365 | |||||||
Dallas 6-6-130% -5½ -110Bet365 | |||||||
![]() Pittsburgh 7-635% -3½ -105Bet365 |
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