Weather Forecast for Carolina Panthers vs San Francisco 49ers

The Monday night football game on November 24, 2025, features the Carolina Panthers visiting the San Francisco 49ers at Levi's Stadium in Santa Clara, CA. This NFL regular season Week 12 matchup promises an intriguing clash of styles and weather conditions that could impact the outcome.

Playing at home, the San Francisco 49ers generally have a strong record at Levi's Stadium, benefitting from familiar surroundings and fan support. The Carolina Panthers, on the road, have shown mixed results in away games, making their performance in this environment crucial. Historically, the 49ers have adapted well to the cooler, partially cloudy weather typical of late November in Northern California, while the Panthers' performance can be affected by colder temperatures, potentially impacting their speed and execution.

Levi's Stadium is an outdoor venue, and the weather forecast for the game indicates partly cloudy skies with temperatures ranging from the mid-50s to low 60s Fahrenheit during the event hours. Winds from the northwest at about 3.6 to 5.4 mph are expected, which could influence passing and kicking games but are not severe enough to cause major disruptions. The chance of rain is minimal, so the game is unlikely to face weather-related delays.

Understanding these weather conditions is vital for bettors as they can affect team performance and game strategy. The 49ers' experience in these conditions may offer them a slight edge, but the Panthers' ability to adapt could shift momentum. Fans and bettors can watch the game on ESPN and use this insight to make informed bets. For more detailed weather updates and betting tips, check out the NFL weather page and consider starting your OddsTrader Turbo subscription or placing a bet with a U.S. regulated sportsbook.