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Get ready for an exciting NFL showdown on December 21, 2025, as the Tampa Bay Buccaneers visit the Carolina Panthers at Bank of America Stadium in Charlotte, NC. This matchup promises thrilling Sunday football action, broadcasted on FOX, where bettors can dive deep into the latest betting trends and game insights.
The Buccaneers, led by starting quarterback Baker Mayfield, face a Panthers defense that ranks strong in pass defense, creating a compelling quarterback advantage scenario. Carolina counters with Andy Dalton at QB, who will look to exploit Tampa Bay's run defense, which has allowed an average of 23.7 rushing yards per game. The Panthers' offensive line, though slightly questionable with some injuries, aims to protect Dalton against the Buccaneers' formidable pass rush led by key defensive ends.
Recent performance stats reveal Tampa Bay's offense averages 203.4 passing yards per game with a solid 33.3 completions per game, while Carolina's defense allows 215.5 passing yards but excels in limiting rushing yards to 116 per game. Tampa Bay's defense gives up 246.9 passing yards and 101.4 rushing yards on average, indicating a balanced defensive challenge for both quarterbacks.
The betting odds favor Tampa Bay as a 3-point favorite with a total points line set at 45.5. This spread suggests a close game where the under bet may be attractive given both teams' recent tendencies towards moderate scoring games. Bettors should consider the Panthers' 8-6 ATS record at home and Tampa Bay's 5-9 ATS away record, as shown on our NFL standings page, for informed wagering.
In their last encounter on December 29, 2024, Tampa Bay dominated Carolina 48-14 at Raymond James Stadium, a result that could influence betting confidence. However, team dynamics and injuries have shifted since then, making this upcoming game less predictable.
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![]() Washington 4-1081% +7 -110Caesars | |||||||
![]() Chicago 10-456% -1 -115SugarHouse | |||||||
Cleveland 3-1162% +10½ -113BetRivers | |||||||
New Orleans 4-1074% -5½ -118FanDuel | |||||||
![]() N.Y. Giants 2-1264% +3 -117BetRivers | |||||||
Carolina 7-771% +3 -110FanDuel | |||||||
![]() Tennessee 2-1281% +3 -110Caesars | |||||||
Dallas 6-7-158% -1½ -115SugarHouse | |||||||
Miami 6-874% +4½ -120FanDuel | |||||||
Arizona 3-1137% +3 -115Bet365 | |||||||
Denver 12-244% -3½ -102FanDuel | |||||||
Detroit 8-614% -6½ -120FanDuel | |||||||
![]() Houston 9-526% -14 -107Caesars | |||||||
![]() Baltimore 7-767% -2½ -121SugarHouse | |||||||
![]() Indianapolis 8-684% +6½ -125BetMGM | |||||||
Seattle 12-338 -1 -115SugarHouse |
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