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Get ready for an exciting NFL showdown on December 21, 2025, as the Tampa Bay Buccaneers take on the Carolina Panthers at Bank of America Stadium in Charlotte, NC. This regular season Week 16 matchup promises intense action and betting opportunities for football fans and sports bettors alike.
The latest odds show the Buccaneers as the favorite with a point spread of -3 -106, while the Panthers are the underdog at +3 -114. Opening odds started similarly, indicating consistent betting interest. The over under is set at 45.5 with the under favored at -112. These betting lines provide valuable insights into how the game is expected to unfold and can help bettors make informed decisions.
Broadcast on FOX, this game offers fans a chance to watch live Sunday football and catch all the thrilling moments. Whether you are a seasoned bettor or new to the game, understanding the odds and betting lines is key to finding value and making smart wagers. Check out the NFL odds page for more details and trends to guide your bets.
Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For those looking for trusted sportsbooks, Caesars offers competitive odds and a great betting experience.
![]() Washington 4-1084% +7 -110Caesars | |||||||
![]() Chicago 10-450% -1 -115SugarHouse | |||||||
Cleveland 3-1155% +10½ -113BetRivers | |||||||
New Orleans 4-1082% -5½ -118FanDuel | |||||||
![]() N.Y. Giants 2-1256% +3 -113Caesars | |||||||
Carolina 7-777% +3 -110Bet365 | |||||||
![]() Tennessee 2-1287% +3 -105BetMGM | |||||||
Dallas 6-7-154% -2 -106Caesars | |||||||
Miami 6-867% +4½ -117SugarHouse | |||||||
Arizona 3-1130% +3 -110Caesars | |||||||
Denver 12-246% -3 -115BetMGM | |||||||
Detroit 8-68% -6½ -120FanDuel | |||||||
![]() Houston 9-533% -14 -110Caesars | |||||||
![]() Baltimore 7-764% -2½ -121SugarHouse | |||||||
![]() Indianapolis 8-683% +6 -110Bet365 | |||||||
Seattle 12-338 -1 -115SugarHouse |
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