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Dec 21, 2025 1:00 PM EST
Week 16
TB
-3 (-105)o45½ (-110)
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Buccaneers vs Panthers Picks Week 16 NFL
Updated:Dec 17, 2025 1:16 AM EST
The upcoming NFL showdown on December 21, 2025, features the Tampa Bay Buccaneers facing off against the Carolina Panthers at Bank of America Stadium in Charlotte, NC. This Sunday football game will be broadcast on FOX and offers exciting betting opportunities for fans and bettors alike.
This match-up is crucial as both teams aim to secure a win in Week 16 of the NFL season. Our expert picks favor the Tampa Bay Buccaneers to win with a predicted score of 23-20 over the Carolina Panthers. The point spread prediction leans slightly towards Carolina with a +3 advantage, but the moneyline and overall confidence favor Tampa Bay.
Our betting tips highlight the under 45.5 total points as the best bet, with a high expected value (EV) of 3.7% and a solid hit rate of 56.1% in recent similar markets. Our prediction model has also been profitable in recent games, with a strong record on the under total bets, helping bettors make smarter wagers.
For those looking to dive deeper, check out our detailed NFL picks page to get more insights and predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Money
Total
TBMoney
CONSENSUS LINE
-162
PROJECTION
CAR (20) - TB (23)
COVER PROBABILITY
EXPECTED VALUE
-1.5%
BET RATING
SEASON COVER %
7/14
50%
OTHER BETS
Sun 12/21 1:00 PMTB @ CAR
Jalen McMillanAnytime Touchdown Scorer
EV
+43.6%
+43.6%
Hunter RenfrowAnytime Touchdown Scorer
EV
+22.3%
+22.3%
Tommy TremblePlayer to score first touchdown
EV
+17.2%
+17.2%
Tez JohnsonAnytime Touchdown Scorer
EV
+17.1%
+17.1%
Sean TuckerPlayer to score first touchdown
EV
+11.5%
+11.5%
Jalen McMillanPlayer to score first touchdown
EV
+10.7%
+10.7%
Bryce YoungPlayer Longest Passing Completion
EV
+10.6%
+10.6%
Sean TuckerAnytime Touchdown Scorer
EV
+9.0%
+9.0%
Bucky IrvingRushing Yards
EV
+7.9%
+7.9%
Devin CulpAnytime Touchdown Scorer
EV
+7.1%
+7.1%
NFL
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This Week
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NFLWeek 16
 Seattle 11-362% +1½ -122FanDuel | |||||||
 Washington 4-1084% +6½ -110Caesars | |||||||
 Chicago 10-433% +1½ -120FanDuel | |||||||
 Cleveland 3-1193% +10½ -115BetRivers | |||||||
 New Orleans 4-1036% -3½ -115SugarHouse | |||||||
 N.Y. Giants 2-1276% +3 -112Caesars | |||||||
 Carolina 7-753% +3 -110Bet365 | |||||||
 Tennessee 2-1256% +3½ -115BetMGM | |||||||
 Dallas 6-7-186% -1½ -120BetMGM | |||||||
 Miami 6-850% +2½ -105BetMGM | |||||||
 Arizona 3-1150% +2½ -105Bet365 | |||||||
 Denver 12-243% -3 -110Bet365 | |||||||
 Detroit 8-615% -6½ -120FanDuel | |||||||
 Houston 9-512% -14 -110Bet365 | |||||||
 Baltimore 7-756% -2½ -122FanDuel | |||||||
 Indianapolis 8-678% +6½ -114Caesars |
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