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The upcoming NFL matchup on November 27, 2025, features the Green Bay Packers visiting the Detroit Lions at Ford Field in Detroit, MI. This Thursday night football game promises great excitement and is broadcast on FOX. Our expert picks favor the Packers with a predicted score of 25 to 22, taking the Green Bay +3 spread. Our prediction model has been profitable over the last 10 games, particularly in the point spread market where we have a strong hit rate and positive EV, making this an excellent betting opportunity. The total points are expected to be under 49.5, aligning with our American Total market insights.
Detroit has shown solid form recently, but Green Bay's strong performance and strategic advantages at Ford Field give them the edge. Bettors looking for reliable predictions and betting tips should consider this game carefully. For more detailed analysis and picks, check out our comprehensive NFL picks page and NFL picks and predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
Philadelphia 8-335% -7 -109Caesars | |||||||
![]() Indianapolis 8-350% -3½ -109Caesars | |||||||
![]() Tampa Bay 6-532% -2½ -120SugarHouse | |||||||
![]() Tennessee 1-1055% +6½ -114FanDuel | |||||||
Carolina 6-660% +10½ -110FanDuel | |||||||
Miami 4-729% -5½ -110Bet365 | |||||||
![]() N.Y. Jets 2-973% +3 -125BetMGM | |||||||
Cleveland 3-829% +5 -110FanDuel | |||||||
Seattle 8-354% -10½ -105FanDuel | |||||||
![]() Pittsburgh 6-577% +3½ -115Caesars | |||||||
![]() L.A. Chargers 7-418% -9 -115SugarHouse | |||||||
![]() Washington 3-835% +6 -114BetRivers | |||||||
New England 10-222% -7 -109Caesars | |||||||
Detroit 7-524 -3 -105BetMGM | |||||||
Dallas 6-5-131 +3½ -110BetMGM | |||||||
![]() Baltimore 6-614 -7½ -114BetRivers |
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