N.Y. Giants vs Detroit Lions Injury Report

The upcoming NFL showdown on November 23, 2025, between the N.Y. Giants and Detroit Lions at Ford Field in Detroit, MI, is set to be a thrilling Sunday football game. This matchup carries significant weight as both teams navigate their player injuries and statuses, which can heavily influence betting strategies.

In the injury report for the N.Y. Giants, several key players are questionable, including defensive lineman Rakeem Nunez-Roches Sr. (toe), wide receiver Darius Slayton (hamstring), and linebacker Demetrius Flannigan-Fowles (illness). Notably, kicker Graham Gano is on injured reserve due to neck soreness, and linebacker Chris Board is also sidelined with a chest injury. These absences could impact the Giants' defensive and special teams performance.

The Detroit Lions face their own challenges with notable players like offensive lineman Graham Glasgow (knee) and tackle Taylor Decker (shoulder) listed as questionable. Linebacker Zach Cunningham is on injured reserve with a hamstring strain, and defensive end Marcus Davenport is in a limited practice status. These injuries may affect the Lions' offensive line stability and defensive pressure.

Understanding the injury list for both teams is crucial for bettors looking to make informed wagers. Player injuries can shift the dynamics of the game, influencing point spreads and prop bets. Fans can catch the game live on Fox, adding to the excitement of this Sunday football event.

For the most up-to-date player statuses and injury details, check out the comprehensive NFL injury report. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.