N.Y. Giants vs Detroit Lions Betting Trends

Get ready for an exciting Sunday football showdown on November 23, 2025, as the N.Y. Giants take on the Detroit Lions at Ford Field in Detroit, MI. This NFL regular season Week 12 game promises to be a thrilling encounter with plenty of betting trends to explore. The Lions, playing at home, are favored with a -13.5 point spread and an under 50.5 total points, indicating a potential defensive battle. Detroit's starting quarterback Jared Goff leads a balanced offense averaging 366.9 total yards per game, with a strong pass offense (236.8 yards/game) and solid run game (130.1 yards/game). The Giants, with Russell Wilson starting at quarterback, bring a slightly less potent offense averaging 333.2 total yards per game but have a slightly better pass defense, which could challenge Detroit's aerial attack.

Both teams have key injuries that could influence the game dynamics. Detroit is missing defensive end Marcus Davenport and linebacker Zach Cunningham, while the Giants are without several defensive starters including Kayvon Thibodeaux. These absences may impact defensive pressure and pass protection, making the matchup's pass rush and pass protection a critical factor for bettors to watch.

Betting insights reveal the Lions' strong home record (3-1 SU and ATS at home) contrasts with the Giants' struggles on the road (0-6 SU away). The Giants have been competitive ATS (6-5), but the Lions' recent form and favorable odds at Caesars make them a compelling favorite. The point spread of -13.5 suggests bettors expect Detroit to control the game, while the total points line at 50.5 hints at a moderately scoring affair.

For bettors looking to dive deeper, this game offers rich betting trends and game stats that can inform smart wagers. The Lions' home advantage, offensive firepower, and defensive resilience against a Giants team battling injuries and road woes suggest the best bet leans towards Detroit covering the spread. Tune into FOX to catch the action live and consider leveraging our OddsTrader Turbo for advanced betting tools. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

In their last matchup on August 8, 2024, the Giants edged out the Lions 14-3 in a preseason battle, setting the stage for this regular season clash. The Lions have a solid 6-4 straight up record this season, while the Giants are struggling at 2-9. Check out the latest odds and team updates to make the most informed bet.