Nov 23, 2025 1:00 PM EST

Week 12

N.Y. Giants

6-4

Detroit

DET

-11½ (-118)o50 (-110)

FOX

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N.Y. Giants vs Detroit Lions Picks

Updated:Nov 22, 2025 2:05 AM EST

The upcoming NFL clash on November 23, 2025, features the N.Y. Giants taking on the Detroit Lions at Ford Field in Detroit, MI. This Sunday football game promises to be a thrilling contest as both teams battle it out in Week 12 of the 2025-26 NFL season. The game will be broadcast on FOX, providing fans and bettors with prime-time access to the action.

Our expert picks favor the Detroit Lions with a predicted score of 29 to 19 over the N.Y. Giants. We recommend betting on the Lions at -11.5 on the point spread, as our model shows a solid 46.7% cover percentage with an expected value of -7.4%, indicating a confident edge. Additionally, the under 50 points total is a smart choice, given the predicted total score is about 48.7, and this market has a hit rate of 52.6% with a positive EV of 0.9% in recent games.

Our NFL predictions have been profitable over the last 10 games, with a strong performance in the American Total market, boasting a hit rate above 50% and positive EV, making these picks valuable for bettors looking to make smart wagering decisions. For more insights and detailed analysis, visit our NFL picks page to enhance your betting strategy.

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/231:00 PM Pittsburgh 6-4 36% +2½ -105Bet365
Chicago 7-3 64% -2½ -114Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/231:00 PM N.Y. Jets 2-8 87% +14 -115Bet365
Baltimore 5-5 13% -13½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/231:00 PM N.Y. Giants 2-9 94% +13 -112BetRivers
Detroit 6-4 6% -11½ -118BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/231:00 PM New England 9-2 51% -7 -105BetMGM
Cincinnati 3-7 49% +7 -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/231:00 PM Seattle 7-3 11% -12½ -110Bet365
Tennessee 1-9 89% +13½ -112FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/231:00 PM Minnesota 4-6 62% +6½ -110Caesars
Green Bay 6-3-1 38% -6½ -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/231:00 PM Indianapolis 8-2 76% +3½ -114Caesars
Kansas City 5-5 24% -3 -120Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/234:05 PM Jacksonville 6-4 61% -2½ -111Caesars
Arizona 3-7 39% +3 -118BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/234:05 PM Cleveland 2-8 52% +4 -109BetRivers
Las Vegas 2-8 48% -3½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/234:25 PM Atlanta 3-7 21% +2½ -112BetRivers
New Orleans 2-8 79% +1 -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/234:25 PM Philadelphia 8-2 65% -3 -110Bet365
Dallas 4-5-1 35% +3½ -121SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/238:20 PM Tampa Bay 6-4 43% +7 -114BetRivers
L.A. Rams 8-2 57% -6½ -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. MON 11/248:15 PM Carolina 6-5 90% +7 +100Bet365
San Francisco 7-4 10% -7 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 11/208:15 PM Buffalo 7-4 19 -4½ -110FanDuel
Houston 6-5 23 +5½ -115SugarHouse

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