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Nov 23, 2025 1:00 PM EST
Week 12
DET
-10½ (-110)o50 (-110)
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N.Y. Giants vs Detroit Lions Picks for NFL Week 12
Updated:Nov 18, 2025 1:23 AM EST
The upcoming NFL regular season Week 12 matchup on November 23, 2025, features the N.Y. Giants visiting the Detroit Lions at Ford Field in Detroit, MI. This Sunday football game will be broadcast live on FOX, making it a prime event for fans and bettors alike. Our expert picks highlight the Detroit Lions as favorites with a predicted score of 28 to the Giants' 20, and a recommended spread bet on Detroit -10.5. The Lions have shown solid form in recent games, and our betting tips are backed by a profitable track record in the last 10 games, especially in the point spread market with a hit rate above 50% and positive EV. The total score is expected to stay under 50.5, aligning with our American Total market insights.
For bettors looking to maximize their edge, this game offers a high EV opportunity on the Detroit moneyline and spread. Our predictions have consistently helped bettors make informed decisions, and with the game being aired on FOX, it's easy to follow the action live. Don't miss out on our detailed NFL picks and predictions to guide your wagers. Check out our comprehensive NFL picks page for more insights and get ready to place your bets with confidence. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Spread
Money
Total
NYGSpread
CONSENSUS LINE
+10½ (-108)
PROJECTION
DET (28) - NYG (20)
COVER PROBABILITY
EXPECTED VALUE
+4.3%
BET RATING
SEASON COVER %
6/11
55%
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NFLWeek 12
 Houston 5-572% +5½ -108Caesars | |||||||
 Chicago 7-354% -3 -104FanDuel | |||||||
 Baltimore 5-514% -13½ -108Caesars | |||||||
 Detroit 6-40% -10½ -110Bet365 | |||||||
 Cincinnati 3-780% +9½ -118BetMGM | |||||||
 Tennessee 1-992% +13½ -110BetMGM | |||||||
 Green Bay 6-3-19% -6½ -109Caesars | |||||||
 Kansas City 5-528% -3 -121SugarHouse | |||||||
 Arizona 3-773% +2½ +100Caesars | |||||||
 Las Vegas 2-875% -3 -125BetMGM | |||||||
 New Orleans 2-873% +1 -115Bet365 | |||||||
 Dallas 4-5-10% +3½ -115Caesars | |||||||
 L.A. Rams 8-239% -6½ -110Bet365 | |||||||
 San Francisco 7-414% -6½ -115Bet365 |
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