Detroit Lions vs Philadelphia Eagles Betting Trends

The upcoming NFL Sunday football game on November 16, 2025, between the Detroit Lions and Philadelphia Eagles at Lincoln Financial Field in Philadelphia, PA, promises an exciting clash in Week 11 of the 2025-26 NFL season. The Philadelphia Eagles, led by starting quarterback Jalen Hurts, come into this game as favorites with a -2.5 point spread and odds of -150 at Caesars sportsbook. Detroit Lions will start Jared Goff at quarterback, looking to overcome the challenge on the road.

Detroit boasts a strong passing offense averaging 236.1 yards per game, facing an Eagles defense that allows 209.3 passing yards. Meanwhile, the Eagles offense averages 191.7 passing yards against a Lions defense allowing 199.7 yards through the air. The Lions' run offense averages 136.3 yards per game, while the Eagles' defense yields 118.6 rushing yards, setting up a balanced matchup. On the defensive side, Eagles have a slightly better pass rush and run defense, which could pressure Lions' quarterback Jared Goff and limit their rushing attack.

Betting trends show both teams have solid ATS records this season, with Detroit at 6-3 and Philadelphia at 6-3 as well. The total points line is set at 46.5, and recent games suggest a moderate scoring affair. Detroit's recent 44-22 win over the Washington Commanders and Philadelphia's 10-7 victory against the Green Bay Packers highlight strong defensive performances. Injuries could impact the game, with several questionable players on both sides, but key starters like Hurts and Goff are expected to play.

This game will be broadcast on NBC and Peacock, giving fans a chance to catch the action live. The odds spread and total points offer valuable betting insights for making smart wagers. The Philadelphia Eagles' home advantage at Lincoln Financial Field and their slightly stronger defense may tip the scales, but Detroit's offensive firepower keeps this contest intriguing. For those looking to bet smarter, consider Start your OddsTrader Turbo subscription or place your wager with a trusted U.S. regulated sportsbook like Caesars.

In their last matchup on September 11, 2022, the Eagles edged the Lions 38-35 in a high-scoring thriller, showing these teams' competitive history and the potential for an exciting game.