Dec 21, 2025 4:25 PM EST

Week 16

Pittsburgh

8-6

Detroit

DET

-7 (-110)o52 (-110)

CBS

MATCHUP PREDICTION ODDS PLAYER PROPS GAME PROPS INJURIES WEATHER

Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.

Don't show me this again

Pittsburgh Steelers vs Detroit Lions Picks

Updated:Dec 19, 2025 1:18 AM EST

The upcoming NFL showdown on December 21, 2025, features the Pittsburgh Steelers visiting the Detroit Lions at Ford Field in Detroit, MI. This Sunday football game promises to be an intense battle as both teams vie for a crucial Week 16 victory. The game will be broadcast live on CBS, providing fans and bettors a prime viewing experience.

Our expert picks favor the Detroit Lions to cover the spread with a predicted score of 28-23 in their favor. The Lions are favored by 7 points, and our model's point spread hit rate stands at 43.7% for Detroit and a more favorable 56.3% for Pittsburgh, but the expected value (EV) leans towards Detroit with -8.3% and 2.8% respectively. The total points are predicted to be just under the 52 mark, with an expected total of 50.9991, aligning with the under 52 bet which holds a 52.6% hit rate and a positive EV of 0.3%.

Our prediction model has been profitable in recent games, especially with the under bet market, which has a solid hit rate and positive EV, making it a smart choice for bettors. This insight, combined with the detailed analysis of team performance and betting trends, should help bettors make informed decisions.

For more detailed NFL picks and predictions, visit our comprehensive NFL picks and predictions page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your wager with a U.S. regulated sportsbook to gain the edge.

When is the Pittsburgh Steelers vs Detroit Lions game?

NFL

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

Spread

Spread
Money
Total
Merged

Game

Game
1H
2H
1Q
2Q
3Q
4Q

This Week

Last Week

Personalize your notifications and get updates on the teams, players or events you care about most. SAT 12/205:00 PM Philadelphia 9-5 16% -6½ -118BetRivers
Washington 4-10 84% +7 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 12/208:20 PM Green Bay 9-4-1 50% +1½ -105Bet365
Chicago 10-4 50% -1 -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/211:00 PM Buffalo 10-4 45% -10½ -105Bet365
Cleveland 3-11 55% +10½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/211:00 PM N.Y. Jets 3-11 18% +6 -109Caesars
New Orleans 4-10 82% -5½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/211:00 PM Minnesota 6-8 44% -2½ -120BetRivers
N.Y. Giants 2-12 56% +3 -113Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/211:00 PM Tampa Bay 7-7 23% -3 -105BetMGM
Carolina 7-7 77% +3 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/211:00 PM Kansas City 6-8 13% -3 -110Caesars
Tennessee 2-12 87% +3 -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/211:00 PM L.A. Chargers 10-4 46% +2½ -112FanDuel
Dallas 6-7-1 54% -2 -106Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/211:00 PM Cincinnati 4-10 33% -4 -108Caesars
Miami 6-8 67% +4½ -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/214:05 PM Atlanta 5-9 70% -2½ -120FanDuel
Arizona 3-11 30% +3 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/214:05 PM Jacksonville 10-4 54% +3½ -110Bet365
Denver 12-2 46% -3 -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/214:25 PM Pittsburgh 8-6 92% +7 -109Caesars
Detroit 8-6 8% -6½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/214:25 PM Las Vegas 2-12 67% +14½ -115BetMGM
Houston 9-5 33% -14 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/218:20 PM New England 11-3 36% +3 -113Caesars
Baltimore 7-7 64% -2½ -121SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. MON 12/228:15 PM San Francisco 10-4 17% -5½ -114Caesars
Indianapolis 8-6 83% +6 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINAL OTTHU 12/188:15 PM L.A. Rams 11-4 37 +2½ -114BetRivers
Seattle 12-3 38 -1 -115SugarHouse

Download the app

NFL

Report

The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.

OddsTrader is licensed to operate in NJ, NY, PA, IN, CO, IA, IL, VA, WV, TN, CT, MI, AZ, LA, WY, OR, KS, DC, MA & OH.

Seek help with a gambling addiction at 1-800-Gambler.

OddsTrader uses cookies to help us provide, protect & improve our services. See ourPrivacy Policyfor more details.

ACCEPT & CLOSE