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FINAL
Dec 21, 2025 4:25 PM EST
PIT 29 vs DET 24
Week 16
DET
-7½ (-116)o52 (-110)
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Pittsburgh Steelers vs Detroit Lions Picks
Updated:Dec 21, 2025 1:24 AM EST
The upcoming NFL matchup between the Pittsburgh Steelers and the Detroit Lions is set for December 21, 2025, at Ford Field in Detroit, MI. This Sunday football game promises to be an exciting event for bettors and fans alike, airing on CBS. Our picks and predictions favor the Detroit Lions to cover the spread with a predicted score of 28-23. The Lions are favored with a -7 point spread, reflecting their strong home performance in a dome environment.
Our betting tips are informed by a solid track record in recent games, particularly in point spread markets where we have seen a profitable hit rate. The American Total market indicates a likely under 52 points total, with a predicted total score close to 50.9, offering bettors a valuable edge. This aligns well with our model's profitable trend over the last 10 games, which has shown strength in spread and total points predictions.
For those looking to dive deeper, our NFL picks page offers comprehensive insights and strategies to maximize your betting success. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Spread
Money
Total
PITSpread
CONSENSUS LINE
+7½ (-114)
PROJECTION
PIT (23) - DET (28)
COVER PROBABILITY
EXPECTED VALUE
+6.9%
BET RATING
SEASON COVER %
7/14
50%
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