Houston Texans vs Indianapolis Colts Betting Trends

The upcoming NFL showdown on November 30, 2025, features the Houston Texans visiting the Indianapolis Colts at Lucas Oil Stadium in Indianapolis, IN. This Sunday football game is a must-watch for bettors and fans alike, broadcast on CBS. Houston's quarterback Davis Mills leads the Texans, while the Colts will start Daniel Jones, stepping in for the injured Anthony Richardson Sr., who is currently on injured reserve after surgery but expected to return later this season.

Houston Texans bring a solid defensive record, ranking strong in pass defense but face challenges against the Colts' potent pass offense, which averages 245.18 yards per game. The Texans' offense has been effective, averaging 323.36 total yards, with Mills showing promise. Indianapolis counters with a robust defense, allowing 342.73 total yards but excelling in pass protection and pass rush, creating an intriguing battle of offensive and defensive lines.

The Colts hold a 3.5-point favorite spread with a total points over/under set at 44.5. Houston's recent form shows resilience with wins over Buffalo and Tennessee, while Indianapolis has a strong home record, undefeated at home with an 8-3 overall standing and 7-4 against the spread. Injuries on both sides could impact gameplay, notably Houston's sidelined key players and the Colts managing without their star QB for now.

Betting trends favor the Colts at home, but Texans' capability to cover spreads cannot be ignored. The game insights suggest a close contest influenced by the Colts' home advantage and quarterback depth. For a detailed look and smarter betting decisions, check out our OddsTrader Turbo subscription or place your bet with a trusted U.S. sportsbook. Don't miss the last matchup on October 27, 2024, where Texans edged Colts 23-20.