Dec 28, 2025 1:00 PM EST

Week 17

Jacksonville

8-7

Indianapolis

JAX

-5½ (-110)o48½ (-110)

FOX

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Jacksonville Jaguars vs Indianapolis Colts Odds

Updated:Dec 28, 2025 1:21 AM EST

The upcoming NFL game on December 28, 2025, between the Jacksonville Jaguars and Indianapolis Colts at Lucas Oil Stadium in Indianapolis, IN, promises to be an exciting Sunday football matchup. Fans and bettors alike will be tuning in to FOX to catch all the action live. This Week 17 regular-season clash offers plenty of opportunities for savvy bettors to capitalize on the latest odds and betting lines.

Currently, the Jacksonville Jaguars are favored with a point spread of -5½ -114, while the Indianapolis Colts sit at +5½ -107 according to Caesars sportsbook. These odds have shifted from the opening lines, which saw the Jaguars at -5 -110 and the Colts at +5 -110. The movement in odds reflects changing public sentiment and insider insights, which are crucial for making informed bets. Additionally, the over/under total is set at 48½ with the over at -110, indicating expectations of a moderately high-scoring game.

Understanding these odds and betting lines can help bettors make smarter decisions. The point spread is especially important for gauging which team is expected to win by a certain margin, while the totals bet offers insight into the anticipated combined score. For those looking to dive deeper into NFL betting, the NFL odds page provides comprehensive information.

Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook like Caesars to get the best odds. This Jacksonville Jaguars vs Indianapolis Colts game is a must-watch for NFL fans and bettors eager to leverage the latest betting insights and maximize their potential winnings.

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/281:00 PM Arizona 3-12 69% +7 -105Bet365
Cincinnati 5-10 31% -7 -108FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/281:00 PM Seattle 12-3 42% -7 -110Bet365
Carolina 8-7 58% +7½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/281:00 PM Pittsburgh 9-6 36% -3½ -105Bet365
Cleveland 3-12 64% +3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/281:00 PM New Orleans 5-10 42% -1½ -110Caesars
Tennessee 3-12 58% +2½ -114FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/281:00 PM Tampa Bay 7-8 16% -5½ -112BetRivers
Miami 6-9 84% +5½ -105Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/281:00 PM Jacksonville 11-4 42% -5½ -110BetMGM
Indianapolis 8-7 58% +6½ -112FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/281:00 PM New England 12-3 44% -13½ -109Caesars
N.Y. Jets 3-12 56% +13½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/284:05 PM N.Y. Giants 2-13 31% -2½ -110FanDuel
Las Vegas 2-13 69% +2½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/284:25 PM Philadelphia 10-5 68% +1½ -105Bet365
Buffalo 11-4 32% -1 -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/288:20 PM Chicago 11-4 71% +3½ -110Bet365
San Francisco 11-4 29% -3 -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. MON 12/298:15 PM L.A. Rams 11-4 16% -8 -110Caesars
Atlanta 6-9 84% +8½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 12/251:00 PM Dallas 7-8-1 30 -8½ -110Bet365
Washington 4-12 23 +9½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 12/254:30 PM Detroit 8-8 10 -7 -114Caesars
Minnesota 8-8 23 +7½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 12/258:15 PM Denver 13-3 20 -13½ -105BetMGM
Kansas City 6-10 13 +13½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FINALSAT 12/274:30 PM Houston 11-5 20 +1½ -110FanDuel
L.A. Chargers 11-5 16 -½ -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. FINALSAT 12/278:00 PM Baltimore 8-8 41 +2½ -110Bet365
Green Bay 9-6-1 24 -2 -117SugarHouse

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