Dec 7, 2025 1:00 PM EST

Week 14

Indianapolis

8-4

Jacksonville

IND

-1½ (-110)o47 (-110)

CBS

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Indianapolis Colts vs Jacksonville Jaguars Picks

Updated:Dec 5, 2025 1:32 AM EST

The upcoming NFL showdown on December 7, 2025, features the Indianapolis Colts visiting the Jacksonville Jaguars at EverBank Stadium in Jacksonville, FL. This Sunday football game promises to be an exciting contest broadcast on CBS. Our expert picks favor the Indianapolis Colts to win with a predicted score of 26-22, covering the spread at -2. Our prediction model has shown strong performance recently, boasting a 55.1% hit rate on the point spread market, which is a profitable angle for bettors looking to capitalize on smart betting decisions.

The total points are expected to go over 46.5, with a predicted total score of approximately 48, adding value for those considering over bets. Jacksonville Jaguars have been competitive but are projected to lose by a narrow margin. With the game taking place in the outdoor EverBank Stadium, weather conditions might slightly influence the gameplay, but both teams are well-prepared for this challenge.

For bettors seeking more comprehensive insights and a broader range of NFL picks, exploring our detailed NFL picks page can provide additional valuable predictions and betting tips. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Washington 3-9 67% +1½ -110Bet365
Minnesota 4-8 33% -1 -120SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Miami 5-7 34% -3 +100Bet365
N.Y. Jets 3-9 66% +3 -114Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Tennessee 1-11 82% +4 -110Bet365
Cleveland 3-9 18% -3½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Pittsburgh 6-6 66% +5½ -105BetMGM
Baltimore 6-6 34% -5½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Seattle 9-3 19% -6½ -115FanDuel
Atlanta 4-8 81% +7 -114Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Indianapolis 8-4 39% -1½ -110Bet365
Jacksonville 8-4 61% +2 -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM New Orleans 2-10 91% +8½ -109Caesars
Tampa Bay 7-5 9% -8½ -108FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Cincinnati 4-8 51% +5½ -105FanDuel
Buffalo 8-4 49% -5½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/074:05 PM Denver 10-2 12% -7½ +100FanDuel
Las Vegas 2-10 88% +7½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/074:25 PM Chicago 9-3 41% +6½ -105Caesars
Green Bay 8-3-1 59% -6½ -110BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/074:25 PM L.A. Rams 9-3 12% -8 -110BetMGM
Arizona 3-9 88% +8½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/078:20 PM Houston 7-5 74% +3½ -117Caesars
Kansas City 6-6 26% -3 -118BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. MON 12/088:15 PM Philadelphia 8-4 23% -2½ -110FanDuel
L.A. Chargers 8-4 77% +2½ -102Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 12/048:15 PM Dallas 6-6-1 30 +3½ -102BetMGM
Detroit 8-5 44 -3½ -102BetMGM

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