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FINAL
Dec 28, 2025 1:00 PM EST
JAX 23 vs IND 17
Week 17
JAX
-4 (-110)o48½ (-110)
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Jacksonville Jaguars vs Indianapolis Colts Picks
Updated:Dec 28, 2025 1:21 AM EST
The upcoming NFL showdown between the Jacksonville Jaguars and the Indianapolis Colts is set for December 28, 2025, at the iconic Lucas Oil Stadium in Indianapolis, IN. This Sunday football event promises to deliver intense action and exciting betting opportunities. Fans can catch the game live on FOX, making it a must-watch for football enthusiasts and bettors alike.
Our expert picks for the Jacksonville Jaguars vs Indianapolis Colts game favor the Jaguars with a predicted score of 25 to 21, suggesting a Jacksonville moneyline bet could be the winning play. The point spread leans slightly towards Indianapolis with a +6.5 advantage, but our model shows a 57.6% hit rate on this spread in recent games, indicating good value. The predicted total score is about 46.23, with a recommendation to bet under 48.5, supported by a 56.9% hit rate and positive EV, making it a solid parlay option.
Over the last 10 games, our prediction model has been profitable, especially on the under market where the hit rate has been strong. This insight can help bettors make smart decisions and capitalize on the edge provided by our detailed analysis. For more NFL picks and predictions, check out our comprehensive NFL picks and predictions page.
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UPCOMING GAME PREDICTION
Spread
Money
Total
INDSpread
CONSENSUS LINE
+4½ (-114)
PROJECTION
IND (21) - JAX (25)
COVER PROBABILITY
EXPECTED VALUE
-0.2%
BET RATING
SEASON COVER %
8/15
53%
NFL
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This Week
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NFLWeek 17
 Atlanta 6-983% +7½ -115Bet365 | |||||||
 Washington 4-1223 +9½ -112BetRivers | |||||||
 Minnesota 8-823 +7½ -110BetMGM | |||||||
 Kansas City 6-1013 +13½ -105BetMGM | |||||||
 L.A. Chargers 11-516 -½ -117SugarHouse | |||||||
 Green Bay 9-6-124 -2 -117SugarHouse | |||||||
 Cincinnati 6-1037 -7 -108FanDuel | |||||||
 Carolina 8-810 +7 -117BetRivers | |||||||
 Cleveland 4-1213 +4½ -114BetRivers | |||||||
 Tennessee 3-1326 +1½ -110Caesars | |||||||
 Miami 7-920 +5½ -105BetMGM | |||||||
 Indianapolis 8-817 +4½ -110FanDuel | |||||||
 N.Y. Jets 3-1310 +13½ -114Caesars | |||||||
 Las Vegas 2-1410 +3 -110BetMGM | |||||||
 Buffalo 11-512 -3 -110BetMGM | |||||||
 San Francisco 12-442 -3½ -112SugarHouse |
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