Indianapolis Colts vs Jacksonville Jaguars Picks

The upcoming NFL regular season Week 14 game on December 7, 2025, features an exciting matchup between the Indianapolis Colts and the Jacksonville Jaguars at EverBank Stadium in Jacksonville, FL. This Sunday football game, broadcasted on CBS, promises plenty of action and betting opportunities for fans and bettors alike.

Our picks and predictions favor the Indianapolis Colts to edge out the Jacksonville Jaguars with a predicted score of 27 to 22, and a point spread of Indianapolis -1.5. The Colts have a solid 57.3% cover percentage on the spread market, showing a positive expected value of 4.9%, which indicates a profitable betting angle for bettors. Meanwhile, the Jaguars have a lower cover percentage and negative EV on their spread, making the Colts the smart bet here.

Our American Total market prediction leans towards the over 47.5 points, with a predicted total score of approximately 48.77. This market has a decent hit rate and a slightly negative EV, but the predicted total score supports a higher scoring game. Bettors looking for insights should consider these stats to make informed decisions.

In recent games, our NFL picks have been profitable, with strong results in the point spread market, winning more than half of our last 10 games, which boosts confidence in this matchup's predictions. Our data-driven approach helps bettors find value and make smart bets.

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