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The upcoming NFL Week 12 matchup on November 23, 2025, between the Indianapolis Colts and Kansas City Chiefs at GEHA Field at Arrowhead Stadium in Kansas City, MO, promises a thrilling Sunday football showdown. The game will be broadcast on CBS, providing fans and bettors with prime-time viewing. An essential aspect for bettors to consider is the injury report, which can heavily influence the game's outcome and betting lines.
The Indianapolis Colts face significant challenges with several key players on injured reserve. Defensive tackle DeForest Buckner is sidelined with a neck injury but is expected to return by mid-December, which is after this game. Quarterback Anthony Richardson Sr. is also on injured reserve due to an orbital fracture but may return soon after this matchup. Other notable Colts on injured reserve include wide receiver D.J. Montgomery, outside linebacker Jacob Phillips, running back Salvon Ahmed, and kicker Spencer Shrader, among others. These injuries to core players could impact the Colts' offensive and defensive capabilities.
On the Kansas City Chiefs' side, safety Deon Bush and defensive end Janarius Robinson are on injured reserve, along with running back Keaontay Ingram and defensive end Felix Anudike-Uzomah. Running back Isiah Pacheco is ruled out for this game due to a knee MCL sprain, which is a significant blow to the Chiefs' rushing attack. Wide receiver Xavier Worthy and tackle Kingsley Suamataia are questionable but expected to play. These player statuses and injuries will be critical for bettors to evaluate before placing wagers.
Understanding the injury report and player statuses for the Indianapolis Colts vs Kansas City Chiefs on November 23, 2025, can provide bettors with an edge in making informed decisions. For the latest and most detailed injury updates, check out the NFL injury report page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() San Francisco 7-421% -7 -115BetRivers | |||||||
![]() Houston 6-523 +5½ -115SugarHouse | |||||||
![]() Chicago 8-331 -2½ -115Bet365 | |||||||
![]() Baltimore 6-523 -13½ -120SugarHouse | |||||||
Detroit 7-434 -13½ -117BetRivers | |||||||
![]() Cincinnati 3-820 +7½ -114Caesars | |||||||
![]() Tennessee 1-1024 +12½ -105BetMGM | |||||||
Green Bay 7-3-123 -6 -117SugarHouse | |||||||
![]() Kansas City 6-523 -4 -115SugarHouse | |||||||
Arizona 3-824 +2½ -114FanDuel | |||||||
![]() Las Vegas 2-910 -3 -110Bet365 | |||||||
New Orleans 2-910 -1½ -105Caesars | |||||||
Dallas 5-5-124 +3 -114Caesars | |||||||
![]() L.A. Rams 9-234 -7 -110BetRivers |
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