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The upcoming NFL regular season Week 12 game on November 23, 2025, features the Indianapolis Colts visiting the Kansas City Chiefs at GEHA Field at Arrowhead Stadium in Kansas City, MO. This Sunday football matchup promises excitement and strategic betting opportunities for fans and bettors alike.
Currently, the Kansas City Chiefs are favored with a point spread of -3½ -106, while the Indianapolis Colts are the underdogs at +3½ -114, according to the best lines at Caesars sportsbook. Opening odds had the Chiefs also favored by 3.5 points, indicating consistent confidence in their home advantage. The total over/under is set at 49½ with the over at -112 and under at -109.
These odds and betting lines are crucial for bettors looking to make informed decisions. The slight movement in moneyline odds, with the Chiefs at -190 and Colts at +155, reflects market sentiment and betting volume shifts. Watching these changes can help bettors find value and leverage their wagers effectively.
Fans can catch this thrilling NFL game on CBS, providing a great viewing experience live from GEHA Field at Arrowhead Stadium. For those wanting an edge, Start your OddsTrader Turbo subscription to analyze odds movements and maximize profits. Alternatively, place your bet with a trusted U.S. regulated sportsbook like Caesars.
Explore more NFL betting options and odds on our NFL odds page to stay ahead of the game and bet smarter this season.
![]() San Francisco 7-421% -7 -115BetRivers | |||||||
![]() Houston 6-523 +5½ -115SugarHouse | |||||||
![]() Chicago 8-331 -2½ -115Bet365 | |||||||
![]() Baltimore 6-523 -13½ -120SugarHouse | |||||||
Detroit 7-434 -13½ -117BetRivers | |||||||
![]() Cincinnati 3-820 +7½ -114Caesars | |||||||
![]() Tennessee 1-1024 +12½ -105BetMGM | |||||||
Green Bay 7-3-123 -6 -117SugarHouse | |||||||
![]() Kansas City 6-523 -4 -115SugarHouse | |||||||
Arizona 3-824 +2½ -114FanDuel | |||||||
![]() Las Vegas 2-910 -3 -110Bet365 | |||||||
New Orleans 2-910 -1½ -105Caesars | |||||||
Dallas 5-5-124 +3 -114Caesars | |||||||
![]() L.A. Rams 9-234 -7 -110BetRivers |
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