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The upcoming NFL showdown between the Indianapolis Colts and Kansas City Chiefs is set for November 23, 2025, at GEHA Field at Arrowhead Stadium in Kansas City, MO. This Sunday football game promises to be a thrilling contest as the Colts visit the Chiefs in a highly anticipated Week 12 matchup. Fans can catch all the action live on CBS, making it a must-watch event for football enthusiasts and bettors alike.
Our picks and predictions favor the Kansas City Chiefs to edge out the Indianapolis Colts with a predicted score of 26 to 23. The Chiefs are favored by 3 points on the spread, but our data suggests that the Colts' +3.5 spread has a higher cover percentage and positive expected value, making it a compelling betting tip for those looking to maximize their returns. The total points are projected to be just under 50.5, with the under bet showing a strong hit rate and positive EV, indicating a tighter, more defensive game.
Recent performance trends show our prediction model has been profitable, especially on the under bet market, winning 6 of the last 10 games, which supports the under 50.5 total points prediction for this game. These stats can help bettors make informed decisions and find an edge in their wagering strategies.
For more detailed NFL picks and betting insights, check out our comprehensive NFL picks and predictions page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() San Francisco 7-421% -7 -115BetRivers | |||||||
![]() Houston 6-523 +5½ -115SugarHouse | |||||||
![]() Chicago 8-331 -2½ -115Bet365 | |||||||
![]() Baltimore 6-523 -13½ -120SugarHouse | |||||||
Detroit 7-434 -13½ -117BetRivers | |||||||
![]() Cincinnati 3-820 +7½ -114Caesars | |||||||
![]() Tennessee 1-1024 +12½ -105BetMGM | |||||||
Green Bay 7-3-123 -6 -117SugarHouse | |||||||
![]() Kansas City 6-523 -4 -115SugarHouse | |||||||
Arizona 3-824 +2½ -114FanDuel | |||||||
![]() Las Vegas 2-910 -3 -110Bet365 | |||||||
New Orleans 2-910 -1½ -105Caesars | |||||||
Dallas 5-5-124 +3 -114Caesars | |||||||
![]() L.A. Rams 9-234 -7 -110BetRivers |
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