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The Sunday football game on December 14, 2025, between the Indianapolis Colts and Seattle Seahawks at Lumen Field in Seattle, WA, promises an exciting NFL Week 15 matchup. The Seahawks, holding a strong home record of 4-2 and leading the league with a 10-3 ATS record, face off against the Colts, who hold a 2-4 away record and a 3-3 ATS record on the road. This game is broadcasted on CBS, making it accessible for fans and bettors alike.
Seattle Seahawks starting quarterback Sam Darnold brings a solid passing offense with 235.6 yards per game, but he faces a Colts defense that allows 246.3 passing yards on average. The Colts will counter with Riley Leonard at QB, who has shown resilience with 237.5 passing yards per game. The Seahawks' defense is slightly tighter, conceding only 197 passing yards per game, which could challenge Leonard's effectiveness. Run offense and defense are balanced, with the Colts averaging 130.9 rushing yards and the Seahawks 117.8, while their defenses allow 98.6 and 91.2 rushing yards respectively.
Seattle's pass rush is notable with 3.15 sacks per game, contrasting with the Colts' 2.69, which might pressure Leonard significantly. The Colts' offensive line, however, has given up only 12.8 sacks, which could provide some protection. The spread is set at Seahawks -13.5, reflecting their favored status, with a total points line of 42.5, suggesting a moderately high-scoring game. These betting trends indicate Seattle's advantage, but the Colts' potential to cover the spread should not be underestimated.
Key players such as Seattle's Cooper Kupp (questionable) and Indianapolis' Quenton Nelson (healthy) will impact the game's flow and betting strategies. The Colts' recent losses and Seattle's strong wins add layers to the betting insights. For a deeper dive into the matchup, check out their last meeting on September 12, 2021, where the Seahawks won 28-16.
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![]() Houston 8-524% -9 -113BetRivers | |||||||
Philadelphia 8-59% -11½ -120FanDuel | |||||||
Jacksonville 9-428% -13 -115Bet365 | |||||||
![]() Chicago 9-422% -7½ -109BetRivers | |||||||
New England 11-255% +1½ -114Caesars | |||||||
![]() Cincinnati 4-955% +2½ -102FanDuel | |||||||
![]() Kansas City 6-735% -5½ -110Bet365 | |||||||
![]() N.Y. Giants 2-1129% -2½ -112Caesars | |||||||
Seattle 10-342% -13½ -115Bet365 | |||||||
Denver 11-224% +2½ -110BetMGM | |||||||
New Orleans 3-1071% +3 -117BetRivers | |||||||
![]() L.A. Rams 10-360% -5½ -117SugarHouse | |||||||
![]() San Francisco 9-411% -12 -115SugarHouse | |||||||
Dallas 6-6-130% -5 -118BetMGM | |||||||
![]() Pittsburgh 7-636% -3 -113Caesars | |||||||
![]() Tampa Bay 7-728 -5½ -112SugarHouse |
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