Nov 16, 2025 1:00 PM EST

Week 11

L.A. Chargers

5-4

Jacksonville

LAC

-3 (-105)o44 (-110)

CBS

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Los Angeles Chargers vs Jacksonville Jaguars Picks

Updated:Nov 14, 2025 1:31 AM EST

The upcoming NFL matchup on November 16, 2025, features the Los Angeles Chargers vs Jacksonville Jaguars at EverBank Stadium in Jacksonville, FL. This Sunday football game promises an exciting showdown broadcasted on CBS, perfect for fans looking to place smart bets. Our expert picks favor the Los Angeles Chargers to win with a predicted score of 24-20, and a slight edge on the Chargers -3 point spread. This prediction aligns with our recent profitable runs, where our 2way market picks have shown a 60.9% hit rate and positive expected value, indicating a strong betting edge.

Jacksonville Jaguars have shown resilience, but the Chargers' recent performance, including a strong win on November 2 against the Tennessee Titans, highlights their capability to cover the spread. Our model also suggests the total points will slightly exceed the line, predicting an over 43.5 with a total score around 44. This insight is valuable for bettors looking to leverage high EV markets like the 2way and point spread bets.

For bettors seeking more detailed NFL picks and predictions, check out our comprehensive NFL picks page where you can find in-depth analysis and betting tips to enhance your wagering strategy. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

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Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/169:30 AM Washington 3-7 37% +2½ +100Caesars
Miami 3-7 63% -2½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Green Bay 5-3-1 19% -7 -110Bet365
N.Y. Giants 2-8 81% +7½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Tampa Bay 6-3 61% +6 -110Caesars
Buffalo 6-3 39% -5½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Cincinnati 3-6 59% +5½ -110Caesars
Pittsburgh 5-4 41% -5½ -108FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Houston 4-5 49% -5½ -112Caesars
Tennessee 1-8 51% +6½ -118SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Chicago 6-3 59% +2½ +100Bet365
Minnesota 4-5 41% -2 -125BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Carolina 5-5 55% +3½ -105BetMGM
Atlanta 3-6 45% -3½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM L.A. Chargers 7-3 54% -3 -105Caesars
Jacksonville 5-4 46% +3 -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/164:05 PM Seattle 7-2 50% +3½ -114Caesars
L.A. Rams 7-2 50% -3 -120Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/164:05 PM San Francisco 6-4 26% -3 -120BetMGM
Arizona 3-6 74% +3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/164:25 PM Baltimore 4-5 35% -7½ -109Caesars
Cleveland 2-7 65% +8 -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/164:25 PM Kansas City 5-4 23% -3½ -120FanDuel
Denver 8-2 77% +4 -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/168:20 PM Detroit 6-3 31% +3 -125BetMGM
Philadelphia 7-2 69% -2½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. MON 11/178:15 PM Dallas 3-5-1 7% -3 -120Bet365
Las Vegas 2-7 93% +3½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 11/138:15 PM N.Y. Jets 2-8 14 +13 -110Caesars
New England 9-2 27 -12½ -110FanDuel

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