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The upcoming NFL showdown on November 16, 2025, features the Los Angeles Chargers visiting the Jacksonville Jaguars at EverBank Stadium in Jacksonville, FL. This Sunday football game is set to be broadcast on CBS and promises an exciting clash between two competitive teams. Our expert picks favor the Chargers with a predicted score of 24 to 20, recommending a bet on the Chargers -3 spread.
Recent prediction trends show a strong hit rate for point spread bets, particularly with the Chargers, who have covered the spread in over half of their last 10 games. Our betting tips highlight the value in the point spread market, which has demonstrated a positive expected value (EV), making it a smart choice for bettors looking to capitalize on this game.
With a predicted total score of approximately 44, the over/under market is also intriguing, but we lean slightly towards the under given recent trends. This matchup at EverBank Stadium provides bettors with multiple profitable betting angles. For more detailed NFL picks and insights, visit our 2025-26 NFL picks page.
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