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The upcoming NFL clash on October 19, 2025, between the Jacksonville Jaguars and L.A. Rams at Wembley Stadium in London is set to be an exciting Sunday football showdown. Jacksonville's starting quarterback Trevor Lawrence leads an offense averaging 207 passing yards and 124 rushing yards per game, while the Rams, with Matthew Stafford at the helm, boast a stronger passing offense at 269 yards per game and a solid rushing attack with 106 yards per game. The Rams are favored by 3 points with a total points line set at 44.5, indicating a moderately competitive game.
Jacksonville's defense allows about 257 passing yards and 92 rushing yards per game, whereas the Rams' defense concedes 199 passing yards and 108 rushing yards, suggesting the Rams have a slight edge in defensive matchups. However, Jacksonville's pass protection and run defense will be tested against a Rams pass rush averaging over 3 sacks per game. Injuries will also play a role; Jacksonville will be without linebacker Devin Lloyd and tight end Quintin Morris, while the Rams are missing offensive lineman Rob Havenstein and wide receiver Puka Nacua.
Recent performances show Jacksonville with a 4-2 record ATS and the Rams also at 4-2 ATS, both teams capable of covering spreads and producing interesting betting trends. The Jaguars have a home ATS record of 3-1, although this game is at a neutral venue. The Rams' recent win over the Baltimore Ravens by 17-3 highlights their defensive prowess. The last encounter in 2021 saw the Rams dominate 37-7 at SoFi Stadium, a game that bettors should consider when looking at this matchup.
Broadcast live on NFL Network, this game offers valuable betting insights. The spread at -3 for the Rams and an over/under of 44.5 points suggest a strategic betting approach focusing on the Rams' passing game and Jacksonville's ground attack. For bettors looking to leverage these betting trends, Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook like Caesars to get the best odds and maximize your winnings.
Jacksonville 4-257% +3 -110Caesars | |||||||
![]() Kansas City 3-335% -11½ -118BetMGM | |||||||
Cleveland 1-541% -2½ -115Caesars | |||||||
![]() Tennessee 1-574% +7 -110Bet365 | |||||||
![]() Chicago 3-241% -4½ -110Bet365 | |||||||
Minnesota 3-277% +2½ -120FanDuel | |||||||
![]() N.Y. Jets 0-649% +1½ -110Bet365 | |||||||
![]() L.A. Chargers 4-252% -1½ -109BetRivers | |||||||
Denver 4-233% -7 -110Bet365 | |||||||
Dallas 2-3-146% -1 -105BetMGM | |||||||
Arizona 2-482% +7 -110Bet365 | |||||||
![]() San Francisco 4-249% -1½ -109BetRivers | |||||||
Detroit 4-228% -5½ -115BetMGM | |||||||
Seattle 4-219% -3 -113Caesars | |||||||
![]() Cincinnati 3-433 +6 -125BetMGM |
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