Kansas City Chiefs vs Tennessee Titans Betting Trends

The upcoming NFL clash on December 21, 2025, between the Kansas City Chiefs and Tennessee Titans at Nissan Stadium in Nashville, TN, promises an exciting Sunday football showdown. The Chiefs, led by starting quarterback Patrick Mahomes who has fully participated in practice, face the Titans with Cam Ward expected to start under center. Despite some questionable injury notes for Tennessee's key players like James Williams Sr. and Kevin Zeitler, the Titans are likely to put up a strong fight at home.

Analyzing the betting trends, Kansas City is favored by 3.5 points with a total points line of 37.5, indicating a relatively low-scoring game. The Chiefs boast a strong passing offense with an average of 244 passing yards per game, while the Titans' pass defense allows about 233 yards, suggesting a competitive aerial battle. On the ground, Kansas City averages 113.9 rushing yards compared to Tennessee's 88.6, with the Titans having a slight edge in run defense. Pass protection for the Chiefs is solid, but Tennessee's pass rush could challenge Mahomes.

Recent form shows Kansas City struggling slightly with a 2-5 record ATS away from home, while Tennessee holds a 3-4 record ATS at home. The Chiefs have lost several close games recently, including a 16-13 loss to the Los Angeles Chargers, while the Titans have mixed results. This matchup is further intensified by their last meeting on November 6, 2022, where the Chiefs edged out the Titans 20-17 in a close contest.

With the game broadcast on CBS, bettors can tune in for live action and use the detailed game insights and betting stats to make informed decisions. The point spread and total points line offer a smart betting angle, especially considering the defensive strengths on both sides. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.