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The Monday night football clash on December 1, 2025, between the N.Y. Giants and New England Patriots at Gillette Stadium in Foxborough, MA, is shaping up to be a thrilling NFL regular season Week 13 game. The Patriots, holding a strong 10-2 record and sitting 1st in the league straight up, face the Giants, who have struggled with a 2-10 record but boast a respectable 7-5 ATS record. Both teams bring contrasting strengths to the field, making this an enticing matchup for bettors.
New England's offense, led by starting quarterback Tommy DeVito, averages 247.5 passing yards per game and 26.5 points, while their defense limits opponents to just 213.5 passing yards and 18.83 points. On the other side, the Giants, starting Jameis Winston at quarterback, average 224 passing yards and 22 points but face challenges with key injuries including cornerback Kayvon Thibodeaux out and linebacker Demetrius Flannigan-Fowles questionable. The Patriots' solid pass protection and aggressive pass rush contrast with the Giants’ middling run offense and defense stats, making the Patriots favorites with a -7 point spread and a total points line set at 46.5.
Recent form favors the Patriots, who have won their last five games, while the Giants have lost their last five. The betting trends highlight New England as the favorite, but the Giants’ ATS record suggests they can cover the spread, especially at home. This game will be broadcast on ESPN, offering fans and bettors alike prime viewing. For detailed game insights and betting stats, this matchup offers a wealth of angles to consider.
In their last matchup on August 21, 2025, the Giants won decisively 42-10 at MetLife Stadium. For more detailed stats and to explore betting opportunities, check out the last Giants vs Patriots game.
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![]() Indianapolis 8-348% -3 -110Caesars | |||||||
![]() Tampa Bay 6-526% -3½ -110BetMGM | |||||||
![]() Tennessee 1-1064% +6½ -120FanDuel | |||||||
Carolina 6-667% +10½ -110Caesars | |||||||
Miami 4-724% -5 -115Bet365 | |||||||
![]() N.Y. Jets 2-973% +3 -105Bet365 | |||||||
Cleveland 3-842% +5½ -105Caesars | |||||||
Seattle 8-343% -10½ -105FanDuel | |||||||
![]() Pittsburgh 6-571% +3 -105Bet365 | |||||||
![]() L.A. Chargers 7-418% -9 -114SugarHouse | |||||||
![]() Washington 3-853% +6½ -105Bet365 | |||||||
New England 10-223% -7 -109Caesars | |||||||
Detroit 7-524 -3 -105BetMGM | |||||||
Dallas 6-5-131 +3½ -110BetMGM | |||||||
![]() Baltimore 6-614 -7½ -114BetRivers | |||||||
Philadelphia 8-415 -7 -110BetMGM |
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