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The upcoming NFL regular season game on December 28, 2025, features the New Orleans Saints visiting the Tennessee Titans at Nissan Stadium in Nashville, Tennessee. This Sunday football matchup is a key Week 17 contest with playoff implications, broadcast on CBS. Bettors can analyze the latest odds to find an edge, with the Titans currently favored by 2.5 points at -107 and the Saints as underdogs at +2.5 with odds of -114. The over/under total is set at 39.5, with the under slightly favored at -112. These betting lines have shifted from their opening positions, indicating market confidence in the Titans' home advantage and defensive strength. Understanding these changes helps bettors make informed decisions and spot value bets.
The New Orleans Saints vs Tennessee Titans odds reflect a competitive game expected to be decided by a narrow margin. The Titans' position as favorites at Nissan Stadium suggests they have the momentum and home crowd advantage. Meanwhile, the Saints' moneyline odds at +125 offer potential for a profitable underdog wager. For those looking to dive deeper, the NFL odds page provides comprehensive betting odds and insights. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() L.A. Chargers 11-469% -1½ -110Bet365 | |||||||
Green Bay 9-5-157% -4 -110Bet365 | |||||||
![]() Cincinnati 5-1040% -7 -110BetRivers | |||||||
Carolina 8-770% +7½ -120FanDuel | |||||||
Cleveland 3-1255% +3 -104Caesars | |||||||
![]() Tennessee 3-1271% +2½ -105Bet365 | |||||||
Miami 6-992% +6 -110BetMGM | |||||||
![]() Indianapolis 8-744% +6½ -110Bet365 | |||||||
![]() N.Y. Jets 3-1244% +13½ -110Bet365 | |||||||
![]() Las Vegas 2-1372% +1½ -118FanDuel | |||||||
Buffalo 11-423% -1 -110Bet365 | |||||||
![]() San Francisco 11-429% -3 -114Caesars | |||||||
![]() Atlanta 6-989% +8½ -118FanDuel | |||||||
![]() Washington 4-1223 +9½ -112BetRivers | |||||||
Minnesota 8-823 +7½ -110BetMGM | |||||||
![]() Kansas City 6-1013 +13½ -105BetMGM |
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