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The upcoming NFL showdown on January 11, 2026, features the San Francisco 49ers visiting the Philadelphia Eagles at Lincoln Financial Field in Philadelphia, PA. This Sunday football game, airing on FOX at 4:30 PM ET, promises excitement and strategic matchups.
Philadelphia Eagles will start quarterback Jalen Hurts, while San Francisco 49ers will rely on Brock Purdy under center. Hurts' dynamic playmaking skills contrast with Purdy's precise passing, setting an intriguing quarterback duel. The Eagles have a strong passing offense averaging 194.3 yards per game, facing the 49ers' defense that allows 232.4 passing yards on average. Conversely, the 49ers’ offense boasts 244.5 passing yards per game against the Eagles’ defense permitting 189.8 yards.
On the ground, the Eagles rush for 116.9 yards per game, slightly edging the 49ers’ 106.9 yards allowed. San Francisco runs for 107.8 yards, challenged by Philadelphia's stout rush defense allowing just 124.4 yards. Pass protection and pass rush battles will be key; the 49ers allow fewer sacks per game (1.6) compared to the Eagles (2.5), while their pass rush generates 2.5 sacks per game against the Eagles’ 2.5.
The point spread favors the Philadelphia Eagles by 6 points (-6 at -105 odds) with an over/under total of 44.5 points. These betting trends suggest a moderately defensive game with the Eagles expected to leverage home advantage. Bettors should consider these betting stats alongside recent performances and injury updates, such as the questionable status of some 49ers players unlikely to impact starting roles. The Eagles have a solid home ATS record of 4-4, while the 49ers excel on the road with 7-2 ATS, visible on our NFL standings page.
For detailed analysis, see their last encounter on December 3, 2023, where the 49ers triumphed 42-19 at Lincoln Financial Field. This game offers valuable game insights to help make an informed wager. Explore the best odds available today for the Philadelphia Eagles and San Francisco 49ers at trusted sportsbooks like BetOnline.
Carolina 8-968% +10½ -108Heritage | |||||||
![]() Chicago 11-628% +2 -105Bovada | |||||||
Jacksonville 13-440% +1 -115BetOnline | |||||||
Philadelphia 11-658% -6 -105BetOnline | |||||||
New England 14-340% -3½ -105BetAnything | |||||||
![]() Pittsburgh 10-761% +3 -108Heritage |