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The upcoming NFL Week 18 game between the Seattle Seahawks and San Francisco 49ers is set for January 3, 2026, at Levi's Stadium in Santa Clara, CA. This Saturday football matchup promises to be intense as both teams look to finish their regular season strong in the 2025-26 NFL season. The game will be broadcast on ABC and ESPN, giving fans and bettors plenty of ways to catch the action live.
In terms of the injury report, the 49ers have several key players listed as questionable, including offensive tackle Trent Williams (knee), tight end George Kittle (hamstring), and defensive lineman Keion White (groin). Fullback Kyle Juszczyk and running back Christian McCaffrey have been participating fully in practice despite previous injuries, which is a positive sign for San Francisco. Defensive line player Yetur Gross-Matos remains out with a knee injury, and wide receiver Ricky Pearsall is questionable with a knee issue.
For the Seahawks, linebacker DeMarcus Lawrence is recovering from a quadriceps injury and did not practice recently, while wide receiver Cooper Kupp is questionable due to hamstring and heel concerns. Offensive lineman Josh Jones has been ruled out due to an ankle injury, and free safety Coby Bryant is doubtful with a foot injury. However, several players like defensive tackle Leonard Williams and wide receiver Rashid Shaheed have been practicing fully or in limited capacity, which could help Seattle's chances.
These injury updates are crucial for bettors to consider when making wagers, as they impact team performance and player availability. Bettors can check the full NFL injury list for more detailed updates and use this information to place smarter bets. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
Minnesota 8-839% -10½ -104FanDuel | |||||||
![]() Houston 11-541% -10½ -110BetRivers | |||||||
![]() Cincinnati 6-1045% -7½ -110BetMGM | |||||||
![]() N.Y. Giants 3-1378% +3½ -112Caesars | |||||||
![]() Atlanta 7-963% -3½ -105Bet365 | |||||||
Jacksonville 12-429% -12½ -115FanDuel | |||||||
New England 13-323% -11½ -105FanDuel | |||||||
![]() Las Vegas 2-1474% +5 -115SugarHouse | |||||||
![]() Chicago 11-553% -3½ -107Caesars | |||||||
Buffalo 11-539% -7½ -118FanDuel | |||||||
Philadelphia 11-546% -4½ -110Caesars | |||||||
![]() L.A. Rams 11-529% -13 -115SugarHouse | |||||||
Denver 13-332% -13½ -120FanDuel | |||||||
![]() Pittsburgh 9-747% +4 -125BetMGM | |||||||
![]() Tampa Bay 8-916 -3 -106FanDuel | |||||||
![]() San Francisco 12-53 +2½ +105Bet365 |
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