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Jan 17, 2026 8:00 PM EST
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-7½ (-110)o45½ (-110)
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San Francisco 49ers vs Seattle Seahawks Betting Trends
Updated:Jan 13, 2026 1:14 AM EST
The upcoming NFL Week 2 showdown between the San Francisco 49ers and Seattle Seahawks is set for January 17, 2026, at Lumen Field in Seattle, WA. This Saturday football game promises intense action as the Seahawks host the 49ers, with the game broadcasted live on Fox. The Seattle Seahawks enter the contest as favorites with a -7.5 point spread and odds of -385 on the moneyline at BetOnline, while the 49ers are the underdogs with +7.5 spread and +306 moneyline odds.
Starting quarterbacks will be Brock Purdy for the 49ers and Sam Darnold for the Seahawks, both expected to play despite some questionable injury statuses on the 49ers' side. The Seahawks have a slight edge in quarterback experience and offensive yardage, averaging 351.35 yards per game compared to the 49ers' 351.41 yards, but the 49ers boast a stronger pass defense, allowing just 232.41 passing yards per game against Seattle's 193.94. The 49ers' run defense (91.94 yards allowed) faces a tough Seahawks rushing attack averaging 123.29 yards per game.
Both teams have solid ATS records, with the 49ers at 12-6 and the Seahawks at 12-5 overall. The total points line is set at 45.5, reflecting expected moderate scoring. Betting trends suggest a competitive matchup with a focus on how each team's pass protection stands against the other's pass rush. The 49ers' offensive line, led by Trent Williams (questionable), will be crucial in protecting Purdy against Seattle's aggressive pass rush.
Recent results show the 49ers winning 23-19 against the Eagles and the Seahawks winning 27-10 against the Panthers. Their last encounter on January 3, 2026, saw Seattle edge out San Francisco 13-3, a low-scoring defensive battle that you can review in detail in their last matchup on January 3, 2026.
These detailed betting insights and game stats can help you make an informed wager. For the best betting odds on this Seattle Seahawks vs San Francisco 49ers game, check out BetOnline. Don't miss out on the action this Saturday night at Lumen Field!
ATS Records
All
12-6 (3rd)Against the Spread12-5 (2nd)
13-5 (8th)Straight Up14-3 (3rd)
+6.5Straight Up Units+4.4
11-7Over / Under9-8
TEAM MATCHUP
OFF
DEF
OFF
DEF
25.7Points28.4
13.3First Half14.2
12.4Second Half14.2
5.6First Quarter6.2
7.7Second Quarter8
5.5Third Quarter7.1
6.8Fourth Quarter6.6
351.4Total Yards351.4
5.7Yards Per Play6.3
244.5Passing Yards228.1
23.4 - 33.8 (69.3%)Completions-Attempts19.1 - 28.3 (67.6%)
6.9Yards Per Passing Play7.6
1.6 (9)Sacks (Yards)1.6 (11)
106.9Rushing Yards123.3
28.3Attempts29.8
3.8Yards Per Rush4.1
22.31st Downs20
13.9Passing10.5
7Rushing7.4
1.4Penalties2.1
6.2 / 12.5 (49.8%)3rd Down4.8 / 12.1 (39.8%)
0.8 / 1.3 (59.1%)4th Down0.4 / 0.7 (58.3%)
2.5 / 3.9 (65.2%)Red Zone1.9 / 3.5 (54.2%)
4.9 (38.3)Penalties (Yards)5.9 (46.6)
0.7Turnovers1.8
0.4Interceptions1.1
0.4Fumbles Lost0.8
63.6Total Plays59.7
5.6Kickoffs6.1
3Returns2.7
81.5Return Yards75.7
27.2Yards Per Return28
2.6Punts3.1
1.5Returns1.7
17.1Return Yards26.4
11.6Yards Per Return15.4
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