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The upcoming NFL showdown on January 4, 2026, features the Seattle Seahawks visiting the San Francisco 49ers at Levi's Stadium in Santa Clara, CA. This Saturday football game promises to be a thrilling conclusion to the regular season, broadcasted on ABC and ESPN for maximum fan engagement.
Our expert picks favor the Seattle Seahawks with a predicted final score of 26-22, backing Seattle -2.5 on the point spread. The total points are expected to stay under 48.5, with a predicted total score of approximately 47.25. Our betting tips highlight the Seahawks' strong recent form, having won 6 of their last 10 games against the spread, demonstrating a solid hit rate and positive EV. This insight offers bettors a smart edge in placing their wagers confidently.
San Francisco 49ers have also shown competitive strength, but our model suggests Seattle has the advantage heading into this crucial Week 18 matchup. For fans looking to sharpen their betting strategy, checking out our detailed NFL picks and predictions can provide valuable guidance. Don't miss out on the best betting opportunities; explore NFL picks and predictions today.
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Minnesota 8-839% -10½ -104FanDuel | |||||||
![]() Houston 11-541% -10½ -110BetRivers | |||||||
![]() Cincinnati 6-1045% -7½ -110BetMGM | |||||||
![]() N.Y. Giants 3-1378% +3½ -112Caesars | |||||||
![]() Atlanta 7-963% -3½ -105Bet365 | |||||||
Jacksonville 12-429% -12½ -115FanDuel | |||||||
New England 13-323% -11½ -105FanDuel | |||||||
![]() Las Vegas 2-1474% +5 -115SugarHouse | |||||||
![]() Chicago 11-553% -3½ -107Caesars | |||||||
Buffalo 11-539% -7½ -118FanDuel | |||||||
Philadelphia 11-546% -4½ -110Caesars | |||||||
![]() L.A. Rams 11-529% -13 -115SugarHouse | |||||||
Denver 13-332% -13½ -120FanDuel | |||||||
![]() Pittsburgh 9-747% +4 -125BetMGM | |||||||
![]() Tampa Bay 8-916 -3 -106FanDuel | |||||||
![]() San Francisco 12-53 +2½ +105Bet365 |
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