- Spread
- Money
- Total
- Merged
Personalize your notifications and get updates on the teams, players or events you care about most.
FINAL
Dec 21, 2025 4:05 PM EST
ATL 26 vs ARI 19
Week 16
ATL
-2½ (-115)o48½ (-105)
FOXBETCAST
PLAYS
MATCHUP
PREDICTION
ODDS
PLAYER PROPS
GAME PROPS
INJURIES
WEATHER
CHAT
Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.
Don't show me this again
Atlanta Falcons vs Arizona Cardinals Odds Week 16
Updated:Dec 21, 2025 1:14 AM EST
The upcoming NFL matchup on December 21, 2025, features the Atlanta Falcons taking on the Arizona Cardinals at State Farm Stadium in Glendale, AZ. This Week 16 game promises to be a thrilling contest as both teams vie for a crucial win in the 2025-26 NFL season. Fans and bettors alike will want to tune in to FOX for full coverage of this Sunday football showdown. Current odds favor the Atlanta Falcons as favorites with a point spread of -3½ -107, compared to the opening spread of -3 -110, indicating a slight shift in betting lines towards the Falcons. The over/under total stands at 48½, with the under favored at -113. These betting odds provide valuable insights for bettors considering their wagers, highlighting the Falcons' slight edge but also the potential for a close game. Arizona Cardinals vs Atlanta Falcons betting lines have evolved since the opening, reflecting market confidence and team performance trends. Bettors should consider these movements carefully to make informed decisions. For those wanting to dive deeper into the NFL betting landscape, our comprehensive NFL odds page offers all the latest odds and updates. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. The best odds available today for the Falcons are -3½ -107 at Caesars, while the Cardinals can be backed at +3 +113 at the same sportsbook. Use these insights to enhance your betting strategy and enjoy a more thrilling NFL experience.
Spread (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
AtlantaSpread
+3.4%
EV
+3.4%
ArizonaSpread
-8.4%
EV
-8.4%
MONEYLINE (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
AtlantaMONEYLINE
+4.9%
EV
+4.9%
ArizonaMONEYLINE
-10.1%
EV
-10.1%
Total (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
OVERTotal
-6.6%
EV
-6.6%
UNDERTotal
+2.0%
EV
+2.0%
Spread (1H)
BEST LINE
AtlantaSpread
ArizonaSpread
MONEYLINE (1H)
BEST LINE
AtlantaMONEYLINE
ArizonaMONEYLINE
Total (1H)
BEST LINE
OVERTotal
UNDERTotal
Spread (2H)
BEST LINE
AtlantaSpread
ArizonaSpread
MONEYLINE (2H)
BEST LINE
AtlantaMONEYLINE
ArizonaMONEYLINE
Total (2H)
BEST LINE
OVERTotal
UNDERTotal
Spread (1Q)
BEST LINE
AtlantaSpread
ArizonaSpread
MONEYLINE (1Q)
BEST LINE
AtlantaMONEYLINE
ArizonaMONEYLINE
Total (1Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (2Q)
BEST LINE
AtlantaSpread
ArizonaSpread
MONEYLINE (2Q)
BEST LINE
AtlantaMONEYLINE
ArizonaMONEYLINE
Total (2Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (3Q)
BEST LINE
AtlantaSpread
ArizonaSpread
MONEYLINE (3Q)
BEST LINE
AtlantaMONEYLINE
ArizonaMONEYLINE
Total (3Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (4Q)
BEST LINE
AtlantaSpread
ArizonaSpread
MONEYLINE (4Q)
BEST LINE
AtlantaMONEYLINE
ArizonaMONEYLINE
Total (4Q)
BEST LINE
OVERTotal
UNDERTotal
NFL
Spread
Game
- Game
- 1H
- 2H
- 1Q
- 2Q
- 3Q
- 4Q
NFLSuper Bowl
Download the app© OddsTrader 2026 All Rights Reserved
The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.
OddsTrader no longer operates under any U.S. license, including Pennsylvania.
Seek help with a gambling addiction at 1-800-Gambler.