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The Minnesota Vikings are set to host the Arizona Cardinals at U.S. Bank Stadium in Minneapolis, MN, on December 1st, 2024, at 1:00 PM EST, broadcasted on FOX. This NFL matchup pits the Vikings, who have a strong 9-2 record straight up, against the Cardinals, who are 6-5 on the season. The Vikings are favored with a -3.5 point spread, and the total points line is set at 45. In their last matchup in August, the Cardinals narrowly edged out the Vikings 18-17. The Vikings boast a formidable home record, which you can see on our NFL standings page. Key players include Arizona's QB Kyler Murray and Minnesota's WR Justin Jefferson, both expected to make significant impacts. With the Vikings' strong home performance and the Cardinals' recent defensive struggles, this game promises to be a thrilling encounter. Bettors should consider the Vikings' home advantage and the Cardinals' inconsistent defensive stats when placing their bets. The Vikings' advantage in passing yards per game could be a deciding factor in this matchup.