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Nov 9, 2025 4:05 PM EST
ARI 22 vs SEA 44
Week 10
SEA
-7 (-115)o45 (-110)
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Arizona Cardinals vs Seattle Seahawks Picks
Updated:Nov 9, 2025 1:15 AM EST
The upcoming NFL regular season Week 10 matchup between the Arizona Cardinals and Seattle Seahawks is set to take place on November 9, 2025, at Lumen Field in Seattle, WA. This Sunday football game promises to be an exciting event for bettors and fans alike, broadcasted on CBS. The Arizona Cardinals will be visiting the Seattle Seahawks in what is expected to be a closely contested game. Our picks favor the Seahawks to cover the 6.5-point spread with a predicted final score of Seattle 26, Arizona 21. The predicted total score is approximately 47, suggesting an over bet on 44.5 could be profitable.
Our prediction model has been performing well recently, with a strong hit rate in point spread bets, particularly for the Arizona Cardinals who have covered 54.8% of the spreads in recent games. The Seahawks have also shown solid form, covering 55.6% of spreads in their last 10 games. These stats provide bettors with confidence in placing smart bets and parlays on this game. For those looking to dive deeper into NFL betting strategies, NFL picks and predictions offer valuable insights to enhance your betting decisions.
Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. The best odds available today for Arizona are ARI Cardinals +6.5 at SugarHouse, and for Seattle, SEA Seahawks -6.5 at SugarHouse.
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