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FINAL
Dec 28, 2025 4:25 PM EST
PHI 13 vs BUF 12
Week 17
BUF
-3 (-118)o45 (-110)
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Buffalo Bills vs Philadelphia Eagles Picks
Updated:Dec 28, 2025 1:34 AM EST
The Buffalo Bills vs Philadelphia Eagles game scheduled for December 28, 2025, at Highmark Stadium in Orchard Park, NY, is a highly anticipated NFL Week 17 matchup. Fans and bettors alike will be tuning in to FOX for this Sunday football showdown. Our expert picks predict a close contest with the Bills narrowly edging out the Eagles by a score of 22-21. The Bills are favored with a spread of -1, reflecting their slight advantage at home.
Our prediction model has been profitable in the last 10 games, especially with point spread bets, boasting a hit rate above 50% and positive expected value. The under 44.5 total points bet also shows a strong edge with a 55.3% hit rate and positive EV, aligning well with our predicted total score of 42.6 points. These stats provide valuable betting tips to help bettors make informed decisions and maximize their chances of winning. For more details and insights on NFL Week 17, check out our comprehensive NFL picks and predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Spread
Money
Total
PHISpread
CONSENSUS LINE
+3 (-109)
PROJECTION
BUF (22) - PHI (20)
COVER PROBABILITY
EXPECTED VALUE
+2.3%
BET RATING
SEASON COVER %
9/15
60%
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