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As NFL fans eagerly await the clash between the Buffalo Bills and Tampa Bay Buccaneers, scheduled for August 23, 2025, anticipation builds for this exciting preseason matchup. Taking place at Raymond James Stadium in Tampa, FL, this game is set to kick off at 7:30 PM ET, and can be streamed live on NFL+. The Bills, coming off a strong performance last season, are looking to continue their momentum. Meanwhile, the Buccaneers are determined to showcase their revamped roster and make a statement on their home turf.
Our prediction model gives the Bills an edge, projecting a 27-21 victory. With a high EV on the spread, bettors might find value in taking the Bills to cover. Historically, our predictions have been profitable, with a 60% hit rate in similar matchups. For those considering American Totals, the over bet has a 53.8% hit rate, suggesting a potentially lucrative opportunity.
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