- Spread
- Money
- Total
- Merged
Personalize your notifications and get updates on the teams, players or events you care about most.
FINAL
Nov 24, 2025 8:15 PM EST
CAR 9 vs SF 20
Week 12
SF
-7½ (-105)o49 (-115)
ESPN, 206BETCAST
PLAYS
MATCHUP
PREDICTION
ODDS
PLAYER PROPS
GAME PROPS
INJURIES
WEATHER
CHAT
Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.
Don't show me this again
Carolina Panthers vs San Francisco 49ers Odds
Updated:Nov 24, 2025 1:29 AM EST
The upcoming NFL showdown on November 24, 2025, features the Carolina Panthers taking on the San Francisco 49ers at Levi's Stadium in Santa Clara, CA. This Monday night football game promises to be a thrilling contest in the 2025-26 season.
Current odds show the San Francisco 49ers as favorites with a point spread of -7½ -106, while the Carolina Panthers are underdogs at +7½ -114. Opening odds were similar, indicating steady confidence in the 49ers maintaining their edge. The over/under total is set at 49½ with the over at -118 and under at -102, suggesting a moderately high-scoring game.
These betting lines provide valuable insights for bettors aiming to make smart wagers. The 49ers' home advantage at Levi's Stadium could be a decisive factor, while the Panthers will look to challenge that dominance. Watching how the odds have moved from opening to current lines can help identify where the market believes value lies.
Fans can catch this exciting NFL matchup live on ESPN. For those interested in exploring more NFL odds, visit our NFL odds page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
Spread (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
CarolinaSpread
-1.0%
EV
-1.0%
San FranciscoSpread
-4.3%
EV
-4.3%
MONEYLINE (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
CarolinaMONEYLINE
+5.4%
EV
+5.4%
San FranciscoMONEYLINE
-7.0%
EV
-7.0%
Total (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
OVERTotal
-5.8%
EV
-5.8%
UNDERTotal
-1.2%
EV
-1.2%
Spread (1H)
BEST LINE
CarolinaSpread
San FranciscoSpread
MONEYLINE (1H)
BEST LINE
CarolinaMONEYLINE
San FranciscoMONEYLINE
Total (1H)
BEST LINE
OVERTotal
UNDERTotal
Spread (2H)
BEST LINE
CarolinaSpread
San FranciscoSpread
MONEYLINE (2H)
BEST LINE
CarolinaMONEYLINE
San FranciscoMONEYLINE
Total (2H)
BEST LINE
OVERTotal
UNDERTotal
Spread (1Q)
BEST LINE
CarolinaSpread
San FranciscoSpread
MONEYLINE (1Q)
BEST LINE
CarolinaMONEYLINE
San FranciscoMONEYLINE
Total (1Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (2Q)
BEST LINE
CarolinaSpread
San FranciscoSpread
MONEYLINE (2Q)
BEST LINE
CarolinaMONEYLINE
San FranciscoMONEYLINE
Total (2Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (3Q)
BEST LINE
CarolinaSpread
San FranciscoSpread
MONEYLINE (3Q)
BEST LINE
CarolinaMONEYLINE
San FranciscoMONEYLINE
Total (3Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (4Q)
BEST LINE
CarolinaSpread
San FranciscoSpread
MONEYLINE (4Q)
BEST LINE
CarolinaMONEYLINE
San FranciscoMONEYLINE
Total (4Q)
BEST LINE
OVERTotal
UNDERTotal
NFL
Spread
Game
- Game
- 1H
- 2H
- 1Q
- 2Q
- 3Q
- 4Q
NFLSuper Bowl
Download the app© OddsTrader 2026 All Rights Reserved
The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.
OddsTrader no longer operates under any U.S. license, including Pennsylvania.
Seek help with a gambling addiction at 1-800-Gambler.