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The Indianapolis Colts are set to host the Chicago Bears on September 22, 2024, at Lucas Oil Stadium in Indianapolis, IN. The game kicks off at 1:00 PM EDT and will be broadcast on CBS. In their last matchup on August 19, 2023, the Colts secured a 24-17 victory over the Bears. The Colts are currently listed as 2-point favorites, with a total points line set at 43.5. The starting quarterback for the Colts is Anthony Richardson, while the Bears will be led by Caleb Williams. Both teams have shown fluctuating performances, with the Bears' offense averaging 17.7 points per game and the Colts' defense allowing 19.3 points per game. For a detailed look at their ATS records, visit our NFL standings page. Key players to watch include Jonathan Taylor for the Colts and DJ Moore for the Bears. Injuries could play a significant role, with the Bears missing key wide receiver Keenan Allen and the Colts' defensive end Samson Ebukam listed on injured reserve. Betting enthusiasts should note the spread and total points as crucial factors in their decision-making process.