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The highly anticipated clash between the Dallas Cowboys and Philadelphia Eagles is set to kick off on September 4, 2025, at Lincoln Financial Field in Philadelphia, PA. This Thursday night football showdown marks the beginning of the 2025-26 NFL season, and fans are eagerly awaiting to see these two powerhouses collide. The Eagles, playing at home, have been dominant in recent encounters, and our prediction model favors them with a 74.8% chance of winning this matchup. The predicted score is Philadelphia 28, Dallas 21, with the total score expected to go over 46.5 points.
The Cowboys, however, are not to be underestimated as they have shown resilience in past games, particularly with a strong performance against the spread. With a 55.8% hit rate on the Dallas +9.5 spread, bettors might find value in backing the Cowboys to cover. The game will be broadcasted on NBC, making it a perfect evening for football enthusiasts to tune in.
Our prediction model has been profitable in the American Total market, winning 6 of the last 10 games. This gives confidence to bettors looking for high EV opportunities. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more detailed predictions and betting tips, check out our NFL picks page.