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Prepare for an electrifying NFL face-off as the Los Angeles Chargers take on the Detroit Lions on July 31st, 2025. Our expert predictions favor the Chargers with a predicted victory of 28-24, highlighting a strong moneyline bet on the Chargers. Historically, our predictions have shown a profitable trend, with the Chargers covering the spread in 64.8% of their recent games, offering a positive expected value (EV) for bettors. Visit our NFL picks page for more detailed insights and to explore our top picks for this matchup.
Seattle - -3½ -110BetOnline | |||||||
![]() L.A. Rams - -3 -120Bovada | |||||||
Jacksonville - -7½ -101Bet105 | |||||||
![]() Cincinnati - -3½ -102Bet105 | |||||||
![]() Indianapolis - +3½ -110BetOnline | |||||||
![]() Pittsburgh - -2½ -122Bet105 | |||||||
![]() Houston - +1½ -120Bovada | |||||||
Carolina - +2½ -102Bet105 | |||||||
![]() Tennessee - -2½ -110Bookmaker | |||||||
Detroit - -7 -105Bet105 | |||||||
![]() L.A. Chargers - -10 -115Bookmaker | |||||||
![]() Las Vegas - -3 -120BetOnline | |||||||
Philadelphia - -4 -103Bet105 | |||||||
Minnesota - +1½ -115Bovada | |||||||
![]() N.Y. Giants - +3 -110MyBookie | |||||||
![]() Kansas City - -2½ -110MyBookie |