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In a thrilling NFL matchup, the Indianapolis Colts will host the Jacksonville Jaguars at Lucas Oil Stadium, Indianapolis, IN, airing live on FOX at 1:00 PM EST on January 5, 2025. Indianapolis is favored by a 3-point spread, while the total points over/under is set at 45. The Colts have a solid home ATS record of 5-2, which you can view on our NFL standings page. In their last matchup on October 6, 2024, the Jaguars triumphed over the Colts with a final score of 37-34. The Colts, led by backup quarterback Joe Flacco due to Anthony Richardson's injury, will look to capitalize on their strong offensive stats, averaging 328.938 total yards per game. Meanwhile, the Jaguars, despite their struggles on the road, will aim to leverage their defensive prowess, having allowed an average of 257.688 passing yards per game.