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The Indianapolis Colts face off against the Pittsburgh Steelers in an exciting Week 4 matchup at Lucas Oil Stadium in Indianapolis, IN. The game will air on CBS at 1:00 PM EDT on September 29, 2024. In their last matchup on December 16, 2023, the Colts triumphed with a score of 30-13. The Colts are currently favored with a +2.5 point spread, and the total points over/under is set at 41. Key players to watch include Colts' quarterback Anthony Richardson, who is questionable but hopeful to play, and Steelers' running back Najee Harris. The Colts have shown strong offensive stats, averaging 131.8 rushing yards per game, while the Steelers have a solid defense, allowing only 21.3 points per game. For more detailed ATS records, check out our NFL standings page. This game promises to be a thrilling encounter with significant implications for both teams.