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FINAL
Sep 21, 2025 1:00 PM EDT
IND 41 vs TEN 20
Week 3
IND
-6 (-110)o42 (-110)
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Indianapolis Colts vs Tennessee Titans Odds
Updated:Sep 21, 2025 3:41 AM EDT
Get ready for a thrilling NFL matchup as the Indianapolis Colts take on the Tennessee Titans on September 21, 2025, at Nissan Stadium in Nashville, TN. The game promises excitement as the Colts, led by their dynamic offense, face off against the Titans' resilient defense. Betting enthusiasts will find this matchup intriguing, especially with the Colts being favored with a -5 spread at -109 odds, while the Titans are at +5 with -112 odds. The over/under is set at 43½ -110, indicating a potentially high-scoring affair.
Catch all the action on CBS and place your bets wisely. The Colts opened as favorites with a -230 Moneyline, while the Titans are at +190, offering enticing odds for those betting on an upset. Observing the movement from the opening odds can guide bettors in making informed decisions. The NFL's regular season is heating up, and this game could have significant implications for both teams' playoff aspirations.
Ready to make your move? Start your OddsTrader Turbo subscription now or check out the latest NFL odds to make a smart bet today. With insights and betting lines, you'll have the edge to profit off this exciting Sunday football clash.
Spread (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
IndianapolisSpread
-12.0%
EV
-12.0%
TennesseeSpread
+8.7%
EV
+8.7%
MONEYLINE (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
IndianapolisMONEYLINE
-11.3%
EV
-11.3%
TennesseeMONEYLINE
+10.0%
EV
+10.0%
Total (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
OVERTotal
-8.1%
EV
-8.1%
UNDERTotal
+1.3%
EV
+1.3%
Spread (1H)
BEST LINE
IndianapolisSpread
TennesseeSpread
MONEYLINE (1H)
BEST LINE
IndianapolisMONEYLINE
TennesseeMONEYLINE
Total (1H)
BEST LINE
OVERTotal
UNDERTotal
Spread (2H)
BEST LINE
IndianapolisSpread
TennesseeSpread
MONEYLINE (2H)
BEST LINE
IndianapolisMONEYLINE
TennesseeMONEYLINE
Total (2H)
BEST LINE
OVERTotal
UNDERTotal
Spread (1Q)
BEST LINE
IndianapolisSpread
TennesseeSpread
MONEYLINE (1Q)
BEST LINE
IndianapolisMONEYLINE
TennesseeMONEYLINE
Total (1Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (2Q)
BEST LINE
IndianapolisSpread
TennesseeSpread
MONEYLINE (2Q)
BEST LINE
IndianapolisMONEYLINE
TennesseeMONEYLINE
Total (2Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (3Q)
BEST LINE
IndianapolisSpread
TennesseeSpread
MONEYLINE (3Q)
BEST LINE
IndianapolisMONEYLINE
TennesseeMONEYLINE
Total (3Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (4Q)
BEST LINE
IndianapolisSpread
TennesseeSpread
MONEYLINE (4Q)
BEST LINE
IndianapolisMONEYLINE
TennesseeMONEYLINE
Total (4Q)
BEST LINE
OVERTotal
UNDERTotal
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