- Spread
- Money
- Total
- Merged
Personalize your notifications and get updates on the teams, players or events you care about most.
FINAL
Sep 5, 2025 8:00 PM EDT
KC 21 vs LAC 27
Week 1
KC
-3 (-110)o47½ (-110)
YoutubeBETCAST
PLAYS
MATCHUP
PREDICTION
ODDS
PLAYER PROPS
GAME PROPS
INJURIES
WEATHER
CHAT
Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.
Don't show me this again
Kansas City Chiefs vs L.A. Chargers Picks
Updated:Sep 5, 2025 4:09 AM EDT
As the 2025-26 NFL season kicks off, the Kansas City Chiefs are set to face the Los Angeles Chargers in a thrilling Friday football matchup on September 5, 2025, at Corinthians Arena in Sao Paulo, Brazil. This game promises to be a captivating start to the season, with both teams eager to establish dominance early on. The Chiefs, led by their dynamic offense, are predicted to edge out the Chargers with a score of 25-20. Our prediction model gives Kansas City a 65.6% win probability, making them the favorites in this encounter. The Chargers, however, are not to be underestimated, as their defense could pose significant challenges. Our best bet for this game is on the Chiefs to cover the -3 spread, with a hit rate of 54.3% and an EV of 0.9%. Historically, our predictions have shown a strong performance in similar matchups, boasting a positive outcome in 6 of the last 10 games. This game will be broadcasted on YouTube, providing fans worldwide with a chance to witness the action live. For more insights and detailed NFL picks, check our NFL picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Spread
Money
Total
KCSpread
CONSENSUS LINE
-3 (-118)
PROJECTION
KC (25) - LAC (20)
COVER PROBABILITY
EXPECTED VALUE
+0.2%
BET RATING
SEASON COVER %
-
-
NFL
Spread
Game
- Game
- 1H
- 2H
- 1Q
- 2Q
- 3Q
- 4Q
NFLSuper Bowl
Download the app© OddsTrader 2026 All Rights Reserved
The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.
OddsTrader no longer operates under any U.S. license, including Pennsylvania.
Seek help with a gambling addiction at 1-800-Gambler.